Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TOP2A | P11388 | 2/20 | 0.33 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Creatinine SCHEMBL11427203 | 0.98 | CRBN (0.48) | CRBNGAATOP2ATOP2BALDH1A1 | |
| Creatinine SCHEMBL20425227 | 0.96 | CRBN (0.47) | CRBNGAATOP2ATOP2BALDH1A1 | |
| Creatinine SCHEMBL14354815 | 0.92 | CRBN (0.50) | CRBNGAATOP2ATOP2BALDH1A1 | |
| Creatinine SCHEMBL14354813 | 0.90 | CRBN (0.48) | CRBNGAATOP2ATOP2BALDH1A1 | |
| Creatinine SCHEMBL27811809 | 0.90 | CRBN (0.52) | CRBNGAATOP2ATOP2BALDH1A1 | |
| Creatinine SCHEMBL15732942 | 0.90 | CRBN (0.52) | CRBNGAATOP2ATOP2BALDH1A1 | |
| Creatinine SCHEMBL28491793 | 0.90 | CRBN (0.56) | CRBNGAATOP2ATOP2BALDH1A1 | |
| Creatinine SCHEMBL2248139 | 0.90 | CRBN (0.56) | CRBNGAATOP2ATOP2BALDH1A1 | |
| Creatinine SCHEMBL7203535 | 0.89 | — | — | |
| Creatinine SCHEMBL8809815 | 0.89 | CRBN (0.61) | CRBNGAATOP2ATOP2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6855337-B1 | Bear derived isolate and method | CARLE DEVELOPMENT FOUNDATION (US) | 2005-02-15 | — | — | US | claimed |
| CN-113555122-B | Predictive model of transient and persistent AKI of severe sepsis patient and construction method thereof | 中南大学湘雅二医院 | 2024-04-26 | — | — | CN | disclosed |
| US-20240123130-A1 | SYSTEM FOR REMOVING UREMIC TOXINS IN DIALYSIS PROCESSES | BAXTER INTERNATIONAL INC. | 2024-04-18 | — | — | US | disclosed |
| CN-115414391-B | Application of lactobacillus plantarum MA2 in preparation of medicine for preventing or improving adenine-induced chronic kidney disease | 天津科技大学 | 2024-03-19 | — | — | CN | disclosed |
| US-11911546-B2 | System for removing uremic toxins in dialysis processes | BAXTER INTERNATIONAL INC. (US) | 2024-02-27 | — | — | US | disclosed |
| CN-116236537-B | Ephedra cough-relieving capsule and production process thereof | 陕西开元制药有限公司 | 2024-01-26 | — | — | CN | disclosed |
| US-11779689-B2 | Blood treatment systems and methods | DEKA PRODUCTS LIMITED PARTNERSHIP (US) | 2023-10-10 | — | — | US | disclosed |
| CN-116421694-A | Application of Dayuan beverage in preparing medicine for preventing or treating intestinal dysbacteriosis and related diseases | 苏州大学 | 2023-07-14 | — | — | CN | disclosed |
| CN-116236537-A | Ephedra cough-relieving capsule and production process thereof | 陕西开元制药有限公司 | 2023-06-09 | — | — | CN | disclosed |
| WO-2023097091-A1 | PARAXANTHINE-BASED COMPOSITIONS FOR ENHANCING MUSCLE FUNCTION, NITRIC OXIDE SIGNALING, AND/OR MUSCLE GLYCOGEN LEVELS | Ingenious Ingredients, LP (US) | 2023-06-01 | — | — | WO | disclosed |
| EP-0051458-B1 | RECIPROCATING DIALYZER HAVING SPACERS | PURDUE RESEARCH FOUNDATION (US) | 1986-09-10 | — | — | EP | disclosed |
| EP-0152640-A2 | Membrane spacer element and reciprocating dialyzer | PURDUE RESEARCH FOUNDATION (US) | 1985-08-28 | — | — | EP | disclosed |
| US-4348283-A | Reciprocating dialyzer having spacers | PURDUE RESEARCH FOUNDATION (US) | 1982-09-07 | — | — | US | disclosed |
| EP-0051458-A2 | Reciprocating dialyzer having spacers | PURDUE RESEARCH FOUNDATION (US) | 1982-05-12 | — | — | EP | disclosed |
| US-4237013-A | Hollow fiber permeability apparatus | NIPPON ZEON CO., LTD. (JP) | 1980-12-02 | — | — | US | disclosed |
| US-4214990-A | Hollow-fiber permeability apparatus | NIPPON ZEON CO. LTD. (JP) | 1980-07-29 | — | — | US | disclosed |
| US-4202776-A | Hollow-fiber permeability apparatus | NIPPON ZEON CO., LTD. (JP) | 1980-05-13 | — | — | US | disclosed |
| US-4187180-A | Hollow-fiber permeability apparatus | NIPPON ZEON CO. LTD. (JP) | 1980-02-05 | — | — | US | disclosed |
| US-4164437-A | LAYERS OF REGENERATED CELLULOSE | AKZO N.V. (NL) | 1979-08-14 | — | — | US | disclosed |
| US-4124510-A | Cross-flow, hollow-fiber permeability apparatus having slit-like inlet means | NIPPON ZEON CO., LTD. (JP) | 1978-11-07 | — | — | US | disclosed |