Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 19/20 | 0.52 |
| ▸ | PPARA | Q07869 | 18/20 | 0.52 |
| ▸ | PPARD | Q03181 | 7/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1336408 | 0.92 | PPARG (0.62) | PPARGPPARAPPARD | |
| SCHEMBL543301 | 0.88 | PPARA (0.51) | PPARGPPARAPPARD | |
| SCHEMBL543393 | 0.85 | PPARA (0.52) | PPARGPPARAPPARD | |
| SCHEMBL6076509 | 0.84 | PPARG (0.54) | PPARGPPARAPPARD | |
| SCHEMBL543946 | 0.82 | PPARA (0.51) | PPARGPPARAPPARD | |
| SCHEMBL543129 | 0.81 | PPARA (0.52) | PPARGPPARAPPARD | |
| SCHEMBL543487 | 0.81 | PPARA (0.62) | PPARGPPARAPPARD | |
| SCHEMBL543503 | 0.79 | PPARA (0.56) | PPARGPPARAPPARD | |
| SCHEMBL542924 | 0.78 | PPARA (0.63) | PPARGPPARAPPARD | |
| Ethane SCHEMBL1834451 | 0.78 | PPARA (0.63) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030236254-A1 | Novel heterocyclic compounds having hypolipidemic, hypocholesteremic activities process for their preparation and pharmaceutical compositions containing them and their use in medicine | CADILA HEALTHCARE LIMITED (IN) | 2003-12-25 | — | — | US | claimed |
| US-7041837-B2 | Heterocyclic compounds having hypolipidemic, hypocholesteremic activities process for their preparation and pharmaceutical compositions containing them and their use in medicine | CADILLA HEALTHCARE LIMITED (IN) | 2006-05-09 | — | — | US | disclosed |
| US-20030236254-A1 | Novel heterocyclic compounds having hypolipidemic, hypocholesteremic activities process for their preparation and pharmaceutical compositions containing them and their use in medicine | CADILA HEALTHCARE LIMITED (IN) | 2003-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030236254-A1 | Novel heterocyclic compounds having hypolipidemic, hypocholesteremic activities process for their preparation and pharmaceutical compositions containing them and their use in medicine | LIPA, LIPC, CYP46A1 | PPARG 129/4885PPARA 68/4885PPARD 143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.