Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 15/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 14/20 | 0.49 |
| ▸ | HTR2C | P28335 | 8/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5227860 | 0.85 | MTNR1A (0.69) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL6077044 | 0.83 | MTNR1A (0.49) | MTNR1AMTNR1B | |
| SCHEMBL6077048 | 0.80 | MTNR1A (0.44) | MTNR1AMTNR1B | |
| SCHEMBL5227065 | 0.74 | MTNR1A (0.70) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL5227741 | 0.73 | MTNR1A (0.59) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL6076698 | 0.73 | MTNR1A (0.64) | MTNR1AMTNR1B | |
| SCHEMBL6086919 | 0.73 | POLB (0.41) | MTNR1AMTNR1B | |
| SCHEMBL6075468 | 0.72 | MTNR1A (0.43) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL6076277 | 0.72 | MTNR1A (0.48) | MTNR1AMTNR1B | |
| SCHEMBL6078382 | 0.71 | MTNR1A (0.38) | MTNR1AMTNR1BHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7126012-B2 | Substituted cyclic compounds | LES LABORATOIRES SERVIER (FR) | 2006-10-24 | — | — | US | disclosed |
| US-7115752-B2 | Substituted cyclic compounds | LES LABORATOIRES SERVIER (FR) | 2006-10-03 | — | — | US | disclosed |
| US-20050124682-A1 | Substituted cyclic compounds | LESIEUR DANIEL (FR) | 2005-06-09 | — | — | US | disclosed |
| US-20050059729-A1 | Substituted cyclic compounds | LESIEUR DANIEL (FR) | 2005-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050059729-A1 | Substituted cyclic compounds | CCNY, CCNT2, TECR | MTNR1A 465/4885MTNR1B 414/4885HTR2C 2198/4885 |
| US-20050124682-A1 | Substituted cyclic compounds | CCNY, CCNT2, TECR | MTNR1A 465/4885MTNR1B 414/4885HTR2C 2198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.