Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6076797 | 0.84 | USP2 (0.69) | HPGDALDH1A1USP2POLBTSHR | |
| SCHEMBL1709325 | 0.81 | HPGD (0.72) | HPGDALDH1A1USP2POLBTSHR | |
| SCHEMBL1107021 | 0.80 | GAA (0.62) | HPGDALDH1A1USP2POLBTSHR | |
| SCHEMBL5248141 | 0.80 | HPGD (0.74) | HPGDALDH1A1USP2POLBTSHR | |
| SCHEMBL5248148 | 0.80 | HPGD (0.74) | HPGDALDH1A1USP2POLBTSHR | |
| SCHEMBL10253878 | 0.79 | GAA (0.60) | HPGDALDH1A1USP2POLBTSHR | |
| SCHEMBL8269659 | 0.79 | USP2 (0.76) | HPGDALDH1A1USP2POLBTSHR | |
| SCHEMBL28741579 | 0.78 | HPGD (0.72) | HPGDALDH1A1USP2POLBTSHR | |
| SCHEMBL13438260 | 0.78 | USP2 (0.93) | HPGDALDH1A1USP2POLBTSHR | |
| SCHEMBL4091917 | 0.78 | HPGD (0.72) | HPGDALDH1A1USP2POLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7098247-B2 | Arylene-carboxylic acid (2-amino-phenyl)-amide derivatives | HOFFMANN-LA ROCHE INC. (US) | 2006-08-29 | — | — | US | disclosed |