Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.73 |
| ▸ | POLB | P06746 | 3/20 | 0.68 |
| ▸ | TSHR | P16473 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | HPGD | P15428 | 6/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.55 |
| ▸ | GRK2 | P25098 | 1/20 | 0.54 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8269659 | 0.85 | USP2 (0.76) | USP2POLBTSHRMAPTHPGD | |
| SCHEMBL13438260 | 0.85 | USP2 (0.93) | USP2POLBTSHRMAPTHPGD | |
| SCHEMBL1709325 | 0.81 | HPGD (0.72) | USP2POLBTSHRMAPTHPGD | |
| SCHEMBL8269685 | 0.81 | USP2 (0.85) | USP2POLBTSHRMAPTHPGD | |
| SCHEMBL6076797 | 0.81 | USP2 (0.69) | USP2POLBTSHRMAPTHPGD | |
| SCHEMBL885325 | 0.81 | POLB (0.68) | USP2POLBTSHRMAPTHPGD | |
| SCHEMBL6076763 | 0.81 | HPGD (0.66) | USP2POLBTSHRMAPTHPGD | |
| SCHEMBL28179817 | 0.81 | USP2 (0.84) | USP2POLBTSHRMAPTHPGD | |
| SCHEMBL17205973 | 0.81 | USP2 (0.84) | USP2POLBTSHRMAPTHPGD | |
| SCHEMBL9784530 | 0.80 | USP2 (0.82) | USP2POLBTSHRMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7098247-B2 | Arylene-carboxylic acid (2-amino-phenyl)-amide derivatives | HOFFMANN-LA ROCHE INC. (US) | 2006-08-29 | — | — | US | disclosed |