Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.75 |
| ▸ | RECQL | P46063 | 1/20 | 0.75 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.56 |
| ▸ | APP | P05067 | 5/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.51 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12360570 | 1.00 | ALDH1A1 (0.75) | ALDH1A1RECQLKCNA3APPPKM | |
| SCHEMBL12360577 | 1.00 | ALDH1A1 (0.75) | ALDH1A1RECQLKCNA3APPPKM | |
| SCHEMBL3705122 | 1.00 | ALDH1A1 (0.75) | ALDH1A1RECQLKCNA3APPPKM | |
| SCHEMBL5067164 | 1.00 | ALDH1A1 (0.75) | ALDH1A1RECQLKCNA3APPPKM | |
| SCHEMBL9063451 | 1.00 | ALDH1A1 (0.75) | ALDH1A1RECQLKCNA3APPPKM | |
| SCHEMBL224480 | 1.00 | ALDH1A1 (0.75) | ALDH1A1RECQLKCNA3APPPKM | |
| SCHEMBL608467 | 1.00 | ALDH1A1 (0.75) | ALDH1A1RECQLKCNA3APPPKM | |
| SCHEMBL12360574 | 1.00 | ALDH1A1 (0.75) | ALDH1A1RECQLKCNA3APPPKM | |
| SCHEMBL21773362 | 1.00 | ALDH1A1 (0.75) | ALDH1A1RECQLKCNA3APPPKM | |
| SCHEMBL11985989 | 1.00 | ALDH1A1 (0.75) | ALDH1A1RECQLKCNA3APPPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5279760-A | Blend of solvent and surfactant | TOHOKU ELECTRIC POWER CO., INC. (JP) | 1994-01-18 | — | — | US | claimed |
| US-3959321-A | PHOSPHATE ANTIOXIDANT | KRAFTCO CORPORATION (US) | 1976-05-25 | — | — | US | claimed |
| US-12036209-B2 | Compounds and methods for the targeted degradation of Interleukin-1 receptor-associated kinase 4 polypeptides | ARVINAS OPERATIONS, INC. (US) | 2024-07-16 | — | — | US | disclosed |
| US-11857519-B2 | Compounds and methods for the targeted degradation of enhancer of zeste homolog 2 polypeptide | ARVINAS OPERATIONS, INC. (US) | 2024-01-02 | — | — | US | disclosed |
| US-20220402907-A1 | MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE | YALE UNIVERSITY | 2022-12-22 | — | — | US | disclosed |
| US-11191741-B2 | Compounds and methods for the targeted degradation of enhancer of zeste homolog 2 polypeptide | ARVINAS OPERATIONS, INC. (US) | 2021-12-07 | — | — | US | disclosed |
| CN-108431194-B | Cleaning agent composition for soldering flux | 花王株式会社 | 2021-02-02 | — | — | CN | disclosed |
| US-20180177750-A1 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF ENHANCER OF ZESTE HOMOLOG 2 POLYPEPTIDE | ARVINAS OPERATIONS, INC. | 2018-06-28 | — | — | US | disclosed |
| EP-2925738-B1 | CARBOXY ESTER KETALS, METHODS OF MANUFACTURE, AND USES THEREOF | GFBIOCHEMICALS LTD (MT) | 2018-01-10 | — | — | EP | disclosed |
| US-9458414-B2 | Cleaning, surfactant, and personal care compositions | GFBIOCHEMICALS LIMITED (MT) | 2016-10-04 | — | — | US | disclosed |
| US-9186878-B2 | Process for making lithographic printing plate | FUJIFILM CORPORATION (JP) | 2015-11-17 | — | — | US | disclosed |
| EP-0967523-B1 | Photosensitive resin composition, method for producing photosensitive resin compsition, and printing plate material | TORAY INDUSTRIES (JP) | 2003-03-19 | — | — | EP | disclosed |
| US-20020144718-A1 | Water-based paint-removing solution | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2002-10-10 | — | — | US | disclosed |
| WO-2002053802-A1 | WATER-BASED PAINT-REMOVING SOLUTION | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2002-07-11 | — | — | WO | disclosed |
| EP-0967523-A1 | Photosensitive resin composition, method for producing photosensitive resin compsition, and printing plate material | TORAY INDUSTRIES, INC. (JP) | 1999-12-29 | — | — | EP | disclosed |
| EP-0656817-A1 | PROCESS FOR DECONTAMINATING SOLID MATERIALS CONTAMINATED WITH ORGANIC POLLUTANTS | FORSCHUNGSZENTRUM JÜLICH GMBH (DE) | 1995-06-14 | — | — | EP | disclosed |
| WO-1994004289-A1 | PROCESS AND PLANT FOR DECONTAMINATING SOLID MATERIALS CONTAMINATED WITH ORGANIC POLLUTANTS | Forschungszentrum Jülich GmbH (DE) | 1994-03-03 | — | — | WO | disclosed |
| US-5279760-A | Blend of solvent and surfactant | TOHOKU ELECTRIC POWER CO., INC. (JP) | 1994-01-18 | — | — | US | disclosed |
| US-4110285-A | Process for the preparation of stable aqueous emulsions of addition polymers and copolymers | SYNRES INTERNATIONAL B.V. (NL) | 1978-08-29 | — | — | US | disclosed |
| US-3959321-A | PHOSPHATE ANTIOXIDANT | KRAFTCO CORPORATION (US) | 1976-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11191741-B2 | Compounds and methods for the targeted degradation of enhancer of zeste homolog 2 polypeptide | CRBN, MDM2, VHL | ALDH1A1 3688/4885RECQL 1851/4885KCNA3 4718/4885 |
| US-12036209-B2 | Compounds and methods for the targeted degradation of Interleukin-1 receptor-associated kinase 4 polypeptides | IRAK1, IRAK4, IRAK2 | ALDH1A1 2211/4885RECQL 1679/4885KCNA3 4796/4885 |
| US-20220402907-A1 | MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE | MDM2, CRBN, VHL | ALDH1A1 2958/4885RECQL 1008/4885KCNA3 4663/4885 |
| US-11857519-B2 | Compounds and methods for the targeted degradation of enhancer of zeste homolog 2 polypeptide | CRBN, MDM2, VHL | ALDH1A1 3688/4885RECQL 1851/4885KCNA3 4718/4885 |
| US-20180177750-A1 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF ENHANCER OF ZESTE HOMOLOG 2 POLYPEPTIDE | CRBN, MDM2, VHL | ALDH1A1 3688/4885RECQL 1851/4885KCNA3 4718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.