Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 15/20 | 0.66 |
| ▸ | LONP1 | P36776 | 13/20 | 0.66 |
| ▸ | PSMB8 | P28062 | 10/20 | 0.66 |
| ▸ | PSMB9 | P28065 | 10/20 | 0.66 |
| ▸ | PSMB6 | P28072 | 10/20 | 0.66 |
| ▸ | PSMB10 | P40306 | 10/20 | 0.66 |
| ▸ | PSMB11 | A5LHX3 | 9/20 | 0.66 |
| ▸ | PSMA7 | O14818 | 9/20 | 0.66 |
| ▸ | PSMB1 | P20618 | 9/20 | 0.66 |
| ▸ | PSMA1 | P25786 | 9/20 | 0.66 |
| ▸ | PSMA2 | P25787 | 9/20 | 0.66 |
| ▸ | PSMA3 | P25788 | 9/20 | 0.66 |
| ▸ | PSMA4 | P25789 | 9/20 | 0.66 |
| ▸ | PSMA5 | P28066 | 9/20 | 0.66 |
| ▸ | PSMB4 | P28070 | 9/20 | 0.66 |
| ▸ | PSMB3 | P49720 | 9/20 | 0.66 |
| ▸ | PSMB2 | P49721 | 9/20 | 0.66 |
| ▸ | PSMA6 | P60900 | 9/20 | 0.66 |
| ▸ | PSMA8 | Q8TAA3 | 9/20 | 0.66 |
| ▸ | PSMB7 | Q99436 | 9/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20093498 | 0.85 | CTSL (0.78) | PSMB5LONP1PSMB8PSMB9PSMB6 | |
| SCHEMBL18848799 | 0.83 | PSMB5 (0.78) | PSMB5LONP1PSMB8PSMB9PSMB6 | |
| SCHEMBL16492912 | 0.83 | PSMB5 (0.78) | PSMB5LONP1PSMB8PSMB9PSMB6 | |
| SCHEMBL464470 | 0.83 | PSMB5 (0.78) | PSMB5LONP1PSMB8PSMB9PSMB6 | |
| SCHEMBL16362648 | 0.83 | PSMB5 (0.78) | PSMB5LONP1PSMB8PSMB9PSMB6 | |
| SCHEMBL21558117 | 0.83 | PSMB5 (0.78) | PSMB5LONP1PSMB8PSMB9PSMB6 | |
| SCHEMBL24390721 | 0.82 | PSMB5 (0.80) | PSMB5LONP1PSMB8PSMB9PSMB6 | |
| SCHEMBL3656124 | 0.82 | CTSL (0.74) | PSMB5LONP1PSMB8PSMB9PSMB6 | |
| SCHEMBL16189897 | 0.82 | PSMB5 (0.80) | PSMB5LONP1PSMB8PSMB9PSMB6 | |
| SCHEMBL1913443 | 0.82 | PSMB5 (0.76) | PSMB5LONP1PSMB8PSMB9PSMB6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110314222-A | Application of the composition of bortezomib and pabishta or Vorinostat in the drug of preparation treatment drug-resistant type MLL leukaemia | 上海交通大学医学院附属瑞金医院 | 2019-10-11 | — | — | CN | disclosed |
| CN-110312727-A | A kind of improved method for preparing borate | 费森尤斯卡比肿瘤学有限公司 | 2019-10-08 | — | — | CN | disclosed |
| CN-110172051-A | IRE-1 alpha inhibitor | 复星弘创(苏州)医药科技有限公司 | 2019-08-27 | — | — | CN | disclosed |
| CN-107082770-B | IRE-1 alpha inhibitor | 复星弘创(苏州)医药科技有限公司 | 2019-04-23 | — | — | CN | disclosed |
| WO-2018150386-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF BORONIC ACID ESTERS | FRESENIUS KABI ONCOLOGY LTD. (IN) | 2018-08-23 | — | — | WO | disclosed |
| US-9353218-B2 | Kit for multifunctional compounds forming crosslinked biomaterials | ANGIOTECH PHARMACEUTICALS, INC. | 2016-05-31 | — | — | US | disclosed |
| US-9326934-B2 | Drug delivery from rapid gelling polymer composition | ANGIOTECH INTERNATIONAL AG | 2016-05-03 | — | — | US | disclosed |
| EP-2181704-B1 | Drug delivery from rapid gelling polymer composition | ANGIOTECH INT AG (CH) | 2015-05-06 | — | — | EP | disclosed |
| US-20130289235-A1 | MULTIFUNCTIONAL COMPOUNDS FOR FORMING CROSSLINKED BIOMATERIALS AND METHODS OF PREPARATION AND USE | ANGIOTECH PHARMACEUTICALS, INC. (CA) | 2013-10-31 | — | — | US | disclosed |
| US-8486437-B2 | Multifunctional compounds for forming crosslinked biomaterials and methods of preparation and use | ANGIOTECH PHARMACEUTICALS (US), INC. (US) | 2013-07-16 | — | — | US | disclosed |
| WO-2005051452-A2 | POLYMER COMPOSITIONS AND METHODS FOR THEIR USE | ANGIOTECH INTERNATIONAL AG (CH) | 2005-06-09 | — | — | WO | disclosed |
| WO-2005051316-A2 | POLYMER COMPOSITIONS AND METHODS FOR THEIR USE | ANGIOTECH INTERNATIONAL AG (CH) | 2005-06-09 | — | — | WO | disclosed |
| WO-2005051444-A2 | SOFT TISSUE IMPLANTS AND ANTI-SCARRING AGENTS | ANGIOTECH INTERNATIONAL AG (CH) | 2005-06-09 | — | — | WO | disclosed |
| WO-2005051483-A2 | ELECTRICAL DEVICES AND ANTI-SCARRING AGENTS | ANGIOTECH INTERNATIONAL AG (CH) | 2005-06-09 | — | — | WO | disclosed |
| WO-2005051871-A2 | IMPLANTABLE SENSORS AND IMPLANTABLE PUMPS AND ANTI-SCARRING AGENTS | ANGIOTECH INTERNATIONAL AG (CH) | 2005-06-09 | — | — | WO | disclosed |
| WO-2005046516-A2 | MEDICAL IMPLANTS AND ANTI-SCARRING AGENTS | ANGIOTECH INTERNATIONAL AG (CH) | 2005-05-26 | — | — | WO | disclosed |
| WO-2005018683-A2 | ANASTOMOTIC CONNECTOR DEVICES | ANGIOTECH INTERNATIONAL AG (CH) | 2005-03-03 | — | — | WO | disclosed |
| US-20040260318-A1 | Anastomotic connector devices | ANGIOTECH INTERNATIONAL AG (CH) | 2004-12-23 | — | — | US | disclosed |
| US-20040225077-A1 | Drug delivery from rapid gelling polymer composition | ANGIOTECH INTERNATIONAL AG (CH) | 2004-11-11 | — | — | US | disclosed |
| WO-2004060346-A2 | DRUG DELIVERY FROM RAPID GELLING POLYMER COMPOSITION | ANGIOTECH INTERNATIONAL AG (CH) | 2004-07-22 | — | — | WO | disclosed |