SCHEMBL60778

SCHEMBL60778

C[C@H](Nc1ccncc1)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.47
MDM2 Q00987 1/20 0.47
TAAR1 Q96RJ0 1/20 0.46
JAK2 O60674 1/20 0.43
TYK2 P29597 1/20 0.43
ROCK2 O75116 4/20 0.42
ROCK1 Q13464 4/20 0.42
KDM4E B2RXH2 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
BCHE P06276 1/20 0.42
MAOA P21397 1/20 0.42
MAOB P27338 1/20 0.42
PTGS2 P35354 1/20 0.42
LMNA P02545 2/20 0.41
HTT P42858 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
EPHX1 P07099 1/20 0.41
DCLK1 O15075 1/20 0.41
CHEK2 O96017 1/20 0.41
GSK3A P49840 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL60777 1.00 GAA (0.47) GAAMDM2TAAR1JAK2TYK2
SCHEMBL503278 1.00 GAA (0.47) GAAMDM2TAAR1JAK2TYK2
SCHEMBL10434559 0.87 KDM4E (0.49) GAATAAR1ROCK2ROCK1KDM4E
SCHEMBL5954539 0.85 TSHR (0.58) L3MBTL1LMNA
SCHEMBL5954535 0.85 TSHR (0.58) L3MBTL1LMNA
SCHEMBL2029540 0.84 SLC7A5 (0.50) KDM4EPTGS2
SCHEMBL10434510 0.84 LMNA (0.52) GAATAAR1KDM4ELMNAHTT
SCHEMBL2028516 0.84 SLC7A5 (0.50) KDM4EPTGS2
SCHEMBL22346275 0.82 MDM2 (0.45) GAAMDM2TAAR1ROCK2ROCK1
SCHEMBL22346276 0.82 MDM2 (0.45) GAAMDM2TAAR1ROCK2ROCK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3808 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12534498-B2 Compounds for use as apelin receptor antagonists CAMBRIDGE ENTERPRISE LIMITED (GB) 2026-01-27 US claimed
US-20250340595-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR TRANSFERRIN RECEPTOR 1 (TfR1) BICYCLETX LTD (GB) 2025-11-06 US claimed
EP-4619043-A1 FIBROBLAST ACTIVATION PROTEIN TARGETED COMPOUNDS AND USE THEREOF Perspective Therapeutics, Inc. (US) 2025-09-24 EP claimed
WO-2025128149-A1 FIBROBLAST ACTIVATION PROTEIN TARGETED COMPOUNDS AND USE THEREOF VIEWPOINT MOLECULAR TARGETING, INC. (US) 2025-06-19 WO claimed
US-20250186630-A1 FIBROBLAST ACTIVATION PROTEIN TARGETING PEPTIDES VIEWPOINT MOLECULAR TARGETING, INC. (US) 2025-06-12 US claimed
US-20250122239-A1 DUAL AGONIST GLP-1 AND NEUROTENSIN FUSION PEPTIDE HOLST BIRGITTE (DK) 2025-04-17 US claimed
WO-2025069009-A1 ROCK2 INHIBITORS IN THE TREATMENT OF OBESITY GRAVITON BIOSCIENCE BV (NL) 2025-04-03 WO claimed
EP-4522221-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF NUCLEIC ACID THERAPEUTICS Entrada Therapeutics, Inc. (US) 2025-03-19 EP claimed
US-20250084142-A1 LONG ACTING PEPTIDE TYROSINE TYROSINE (PYY) ANALOGS AND METHODS OF USE I2O THERAPEUTICS INC (US) 2025-03-13 US claimed
WO-2025050100-A1 COMPOSITIONS AND METHODS FOR TREATING HAIR AND SKIN CONDITIONS RELATED TO FOLLICULOPILOSEBACEOUS UNITS OLSEN ELISE A (US) 2025-03-06 WO claimed
EP-0989136-A1 PEPTIDES HAVING CYCLIC STRUCTURES AND EXERTING P53 PROTEIN ACTIVTY-RESTORING EFFECT ON P53 PROTEIN MUTANTS KYOWA HAKKO KOGYO CO., LTD. (JP) 2000-03-29 EP claimed
EP-0646596-B1 Nucleic acid binding oligomers having C-branches for therapy and diagnosis BAYER AG (DE) 1999-05-26 EP claimed
EP-0646595-B1 Nucleic acid binding oligomers having C-branches for therapy and diagnosis BAYER AG (DE) 1998-11-04 EP claimed
US-5623049-A FLEXIBLE ANTISENSE AGENTS COMPRISING OLIGONUCEOTIDES HAVING THE (DEOXY)RIBOSE BACKBONE REPLACED BY AN OLIGOPEPTIDE; PROTEASE- AND NUCLEASE-RESISTANT; VIRICIDES; ATTACHED TO CARRIERS ABLE TO PENETRATATE IN CELLS BAYER AKTIENGESELLSCHAFT (DE) 1997-04-22 US claimed
EP-0700928-A1 Nucleic acid-binding oligomers for therapy and diagnostics BAYER AG (DE) 1996-03-13 EP claimed
EP-0646596-A1 Nucleic acid binding oligomers having C-branches for therapy and diagnosis BAYER AG (DE) 1995-04-05 EP claimed
EP-0646595-A1 Nucleic acid binding oligomers having C-branches for therapy and diagnosis BAYER AG (DE) 1995-04-05 EP claimed
EP-0417698-A2 Amino acid derivatives having renin-inhibiting activity, process for their preparation, agents containing them, and their use HOECHST AKTIENGESELLSCHAFT (DE) 1991-03-20 EP claimed
EP-0394829-A1 Renin-inhibiting dipeptides, process to synthetize them, compositions containing them and their use HOECHST AKTIENGESELLSCHAFT (DE) 1990-10-31 EP claimed
EP-0394853-A1 Dipeptide-derivatives with enzym-inhibiting activity HOECHST AKTIENGESELLSCHAFT (DE) 1990-10-31 EP claimed