Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 18/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6079327 | 0.74 | KCNH2 (0.44) | KCNH2 | |
| SCHEMBL4514214 | 0.74 | KCNH2 (0.42) | KCNH2 | |
| SCHEMBL4436095 | 0.73 | KCNH2 (0.52) | KCNH2 | |
| SCHEMBL3229809 | 0.73 | KCNH2 (0.52) | KCNH2 | |
| SCHEMBL5745688 | 0.71 | KCNH2 (0.50) | KCNH2 | |
| SCHEMBL4512794 | 0.70 | KCNH2 (0.42) | KCNH2 | |
| SCHEMBL4144862 | 0.70 | KCNH2 (0.49) | KCNH2 | |
| SCHEMBL6079826 | 0.69 | KCNH2 (0.38) | KCNH2 | |
| Bicarbonate SCHEMBL4039850 | 0.69 | KCNH2 (0.45) | KCNH2 | |
| SCHEMBL5260537 | 0.69 | KCNH2 (0.54) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060041123-A1 | Antibacterial agents | GLAXO GROUP LIMITED (GB) | 2006-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060041123-A1 | Antibacterial agents | NQO2, NRDC, IFNG | KCNH2 3365/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.