SCHEMBL607945

SCHEMBL607945

COc1c(F)c(F)cc(C(=O)O)c1F

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.44
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
LMNA P02545 1/20 0.41
MAPK1 P28482 1/20 0.41
HTT P42858 1/20 0.41
RAB9A P51151 1/20 0.41
MAPT P10636 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
PKM P14618 1/20 0.39
KEAP1 Q14145 1/20 0.39
NFE2L2 Q16236 1/20 0.39
LCK P06239 1/20 0.39
FYN P06241 1/20 0.39
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38
GFER P55789 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
TSHR P16473 1/20 0.38
HSD17B1 P14061 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27927680 0.98 HSD17B10 (0.43) HSD17B10MEN1KMT2ALMNAMAPK1
Ethylene Glycol SCHEMBL2829965 0.93 HSD17B10 (0.40) HSD17B10MEN1KMT2ALMNAMAPK1
Methylene Chloride SCHEMBL28420789 0.93 HSD17B10 (0.40) HSD17B10MEN1KMT2ALMNAMAPK1
SCHEMBL28937179 0.92 HSD17B10 (0.39) HSD17B10MEN1KMT2ALMNAMAPK1
SCHEMBL28937180 0.92 HSD17B1 (0.47) HSD17B10MEN1KMT2ALMNAMAPK1
SCHEMBL2831144 0.92 HSD17B10 (0.39) HSD17B10MEN1KMT2ALMNAMAPK1
1,3-Propanediol SCHEMBL2834709 0.90 HSD17B10 (0.38) HSD17B10MEN1KMT2ALMNAMAPK1
1,4-Butanediol SCHEMBL2831393 0.90 HSD17B10 (0.38) HSD17B10MEN1KMT2ALMNAMAPK1
Biphenyl SCHEMBL2838222 0.90 AKR1C2 (0.47) MEN1KMT2ACYP2C9TSHRNR1H2
SCHEMBL2838557 0.89 HSD17B10 (0.37) HSD17B10MEN1KMT2ALMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 235 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115536526-B Method for continuously preparing 2,4, 5-trifluoro-3-methoxybenzoic acid by tubular reactor 福建华药生物技术有限公司 2024-12-03 CN claimed
CN-117191966-A Method for detecting 2,4, 5-trifluoro-3-methoxybenzoic acid in moxifloxacin hydrochloride 山东鲁抗医药股份有限公司 2023-12-08 CN claimed
CN-116042493-B Bacillus cereus, microbial inoculum, application of bacillus cereus and microbial inoculum in treatment of chemical wastewater and treatment device 江苏聚庚科技股份有限公司 2023-09-12 CN claimed
CN-116042493-A Bacillus cereus, microbial inoculum, application of bacillus cereus and microbial inoculum in treatment of chemical wastewater and treatment device 江苏聚庚科技股份有限公司 2023-05-02 CN claimed
CN-111635307-B 2,4,5-trifluoro-3-methoxybenzoyl chloride synthesis method 浙江华基生物技术有限公司 2023-03-31 CN claimed
CN-114736133-B Preparation of 2,4, 5-trifluoro-3-methoxybenzoic acid 内蒙古源宏精细化工有限公司 2023-03-24 CN claimed
CN-115536526-A Method for continuously preparing 2,4, 5-trifluoro-3-methoxybenzoic acid by tubular reactor 福建华药生物技术有限公司 2022-12-30 CN claimed
CN-111253241-B 2,4,5-trifluoro-3-methoxybenzoyl chloride and preparation method of intermediate thereof 浙江新和成股份有限公司 2022-11-04 CN claimed
CN-114736133-A Preparation of 2,4, 5-trifluoro-3-methoxybenzoic acid 内蒙古源宏精细化工有限公司 2022-07-12 CN claimed
CN-110878082-B Gatifloxacin and its synthesis method 怀化学院 2021-06-01 CN claimed
CN-111662172-A Process for preparing 2,4, 5-trifluoro-3-methoxybenzoic acid by one-pot method 浙江华基生物技术有限公司 2020-09-15 CN claimed
CN-111635307-A Synthesis method of 2,4, 5-trifluoro-3-methoxybenzoyl chloride 浙江华基生物技术有限公司 2020-09-08 CN claimed
CN-111253241-A Preparation method of 2,4, 5-trifluoro-3-methoxybenzoyl chloride and intermediate thereof 浙江新和成股份有限公司 2020-06-09 CN claimed
CN-110878082-A Gatifloxacin and its synthesis method 怀化学院 2020-03-13 CN claimed
CN-106279257-A A kind of dibutyl tin 2,4,5 trifluoro 3 methoxybenzoic acid ester coordination compound of stannum oxa-ring structure and preparation method and application 衡阳师范学院 2017-01-04 CN claimed
US-5380926-A Reacting a tetrafluorophthalimide with alkali metal hydroxide to form alkali salts of 4-hydroxy-3,5,6-trifluorophthalamic acids and 3-hydroxy-2,4,5-trifluorobenzamides, methylation, acidification, decarboxylation OCCIDENTAL CHEMICAL CORPORATION (US) 1995-01-10 US claimed
JP-7278051-A None JP disclosed
JP-7278051-A None JP disclosed
US-4980470-A 8-alkoxyquinolonecarboxylic acid and salts thereof KYORIN PHARMACEUTICAL CO., LTD. (JP) 1990-12-25 US disclosed
EP-0230295-A2 8-alkoxyquinolonecarboxylic acid and salts thereof excellent in the selective toxicity and process of preparing the same KYORIN PHARMACEUTICAL CO., LTD. (JP) 1987-07-29 EP disclosed