SCHEMBL607964

SCHEMBL607964

CCCCCN(C(C)=O)c1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.67
RAB9A P51151 2/20 0.67
PAX8 Q06710 2/20 0.67
JAK2 O60674 1/20 0.67
TP53 P04637 3/20 0.54
ALDH1A1 P00352 7/20 0.52
TSHR P16473 2/20 0.52
GLA P06280 1/20 0.52
CHRM2 P08172 1/20 0.49
CHRM1 P11229 1/20 0.49
CHRM3 P20309 1/20 0.49
TACR1 P25103 1/20 0.49
ELANE P08246 1/20 0.48
GPX4 P36969 1/20 0.48
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1208763 0.98 NPC1 (0.69) NPC1RAB9APAX8JAK2TP53
SCHEMBL9809230 0.98 NPC1 (0.69) NPC1RAB9APAX8JAK2TP53
SCHEMBL817611 0.95 NPC1 (0.59) NPC1RAB9APAX8JAK2TP53
SCHEMBL3918023 0.91 NPC1 (0.61) NPC1RAB9APAX8JAK2TP53
SCHEMBL10902389 0.89 NPC1 (0.59) NPC1RAB9APAX8JAK2TP53
SCHEMBL10960951 0.87 NPC1 (0.69) NPC1RAB9APAX8JAK2TP53
SCHEMBL894066 0.87 NPC1 (0.69) NPC1RAB9APAX8JAK2TP53
SCHEMBL2069635 0.87 TP53 (0.59) NPC1RAB9APAX8JAK2TP53
SCHEMBL10960608 0.86 NPC1 (0.71) NPC1RAB9APAX8JAK2TP53
SCHEMBL10961189 0.86 NPC1 (0.71) NPC1RAB9APAX8JAK2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1052 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110200549-A1 Organic Compounds Suitable For Modulating Fragrance Compositions GIVAUDAN SA (CH) 2011-08-18 US claimed
EP-2342180-A2 ORGANIC COMPOUNDS SUITABLE FOR MODULATING FRAGRANCE COMPOSITIONS Givaudan SA (CH) 2011-07-13 EP claimed
WO-2010037244-A2 ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2010-04-08 WO claimed
US-7148280-B2 Polymer microspheres containing latent colorants and method of preparation EASTMAN KODAK COMPANY (US) 2006-12-12 US claimed
US-6914106-B2 Polymer microspheres containing latent colorants and method of preparation EASTMAN KODAK COMPANY (US) 2005-07-05 US claimed
US-20050027045-A1 POLYMER MICROSPHERES CONTAINING LATENT COLORANTS AND METHOD OF PREPARATION EASTMAN KODAK COMPANY 2005-02-03 US claimed
US-20050020786-A1 Polymer microspheres containing latent colorants and method of preparation EASTMAN KODAK COMPANY 2005-01-27 US claimed
US-6620580-B2 Photographic element comprising a support bearing a blue light sensitive record containing at least three layers having different levels of light sensitivity arranged in the order slowest to fastest with the slowest layer closest to the EASTMAN KODAK COMPANY 2003-09-16 US claimed
US-20030143498-A1 Color negative element containing triple-coated blue record and method of imaging using same EASTMAN KODAK COMPANY 2003-07-31 US claimed
EP-1014184-B1 Photographic element containing a dir coupler EASTMAN KODAK CO (US) 2003-02-26 EP claimed
EP-0017833-B1 COLOUR-PHOTOGRAPHIC RECORDING MATERIAL CONTAINING A YELLOW COUPLER Agfa-Gevaert AG (DE) 1982-01-20 EP claimed
EP-0030747-A1 2-Equivalent yellow-forming colour couplers, their use in the production of photographic colour images, and photographic elements containing such couplers AGFA-GEVAERT N.V. (BE) 1981-06-24 EP claimed
US-4201584-A Silver halide elements containing yellow forming color couplers for silver halide photography AGFA-GEVAERT N.V. (BE) 1980-05-06 US claimed
EP-0001650-A1 Acylacetanilide compounds and their use as yellow forming colour couplers for silver halide photography AGFA-GEVAERT N.V. (BE) 1979-05-02 EP claimed
US-4057432-A PHOTOGRAPHIC COUPLERS KONISHIROKU PHOTO INDUSTRY CO., LTD. (JA) 1977-11-08 US claimed
US-RE29379-E FUSED-RING DIAZOLE OR TRIAZOLE CONTAINING COUPLER FUJI PHOTO FILM CO., LTD. (JA) 1977-08-30 US claimed
US-4008086-A PYRIDONE OR PYRIDAZONE DERIVATIVES KONISHIROKU PHOTO INDUSTRY CO., LTD. (JA) 1977-02-15 US claimed
US-3973968-A YELLOW KONISHIROKU PHOTO INDUSTRY CO., LTD. (JA) 1976-08-10 US claimed
US-3933500-A Color photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JA) 1976-01-20 US claimed
US-3930863-A MULTILAYER, HYDROQUINONE DERIVATIVES FUJI PHOTO FILM CO., LTD. (JA) 1976-01-06 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110200549-A1 Organic Compounds Suitable For Modulating Fragrance Compositions CYP2A6, CYP2B6, CYP2A13 NPC1 3110/4885RAB9A 4590/4885PAX8 2828/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.