Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.69 |
| ▸ | RAB9A | P51151 | 2/20 | 0.69 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.69 |
| ▸ | JAK2 | O60674 | 1/20 | 0.69 |
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | TACR1 | P25103 | 1/20 | 0.50 |
| ▸ | GPX4 | P36969 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7995028 | 0.98 | NPC1 (0.71) | NPC1RAB9APAX8JAK2TP53 | |
| SCHEMBL8032558 | 0.98 | NPC1 (0.71) | NPC1RAB9APAX8JAK2TP53 | |
| SCHEMBL5509984 | 0.98 | NPC1 (0.71) | NPC1RAB9APAX8JAK2TP53 | |
| SCHEMBL7469093 | 0.98 | NPC1 (0.71) | NPC1RAB9APAX8JAK2TP53 | |
| SCHEMBL2892022 | 0.94 | NPC1 (0.61) | NPC1RAB9APAX8JAK2TP53 | |
| SCHEMBL5154776 | 0.90 | ADRA2C (0.55) | NPC1RAB9APAX8JAK2TP53 | |
| SCHEMBL10960951 | 0.89 | NPC1 (0.69) | NPC1RAB9APAX8JAK2TP53 | |
| SCHEMBL17473048 | 0.88 | NPC1 (0.57) | NPC1RAB9APAX8JAK2TP53 | |
| SCHEMBL30957362 | 0.88 | NPC1 (0.57) | NPC1RAB9APAX8JAK2TP53 | |
| SCHEMBL10960608 | 0.87 | NPC1 (0.71) | NPC1RAB9APAX8JAK2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0097564-B1 | PROCESS FOR THE HYDROXYLATION OF PHENOL AND ANILINE DERIVATIVES BY HYDROGEN PEROXIDE IN A SUPERACIDIC MEDIUM | ELF ATOCHEM S.A. (FR) | 1985-11-13 | — | — | EP | claimed |
| JP-62185004-A | — | — | None | — | — | JP | disclosed |
| JP-8225415-A | — | — | None | — | — | JP | disclosed |
| JP-55081803-A | — | — | None | — | — | JP | disclosed |
| JP-55081802-A | — | — | None | — | — | JP | disclosed |
| EP-2132987-B1 | NEMATICIDAL AGENT COMPOSITION AND METHOD OF USING THE SAME | NIHON NOHYAKU CO LTD (JP) | 2016-04-06 | — | — | EP | disclosed |
| EP-2361503-B1 | N-2-(hetero)arylethylcarboxamide derivative, and pest-controlling agent comprising the same | NIHON NOHYAKU CO LTD (JP) | 2015-05-27 | — | — | EP | disclosed |
| US-20140243340-A1 | CYTOCHROME P450 OXIDASE INHIBITORS AND USES THEREOF | ABBVIE INC. (US) | 2014-08-28 | — | — | US | disclosed |
| US-8648101-B2 | Nematicidal agent composition and method of using the same | NIHON NOHYAKU CO., LTD. (JP) | 2014-02-11 | — | — | US | disclosed |
| US-20130131085-A1 | CYTOCHROME P450 OXIDASE INHIBITORS AND USES THEREOF | ABBOTT LABORATORIES (US) | 2013-05-23 | — | — | US | disclosed |
| JP-S62185004-A | INSECTICIDAL COMPOSITION FOR LISSORHOPTRUS ORYZOPHILUS | YASHIMA CHEM IND CO LTD | 1987-08-13 | — | — | JP | disclosed |
| EP-0103114-B1 | THIENOPYRIDINE DERIVATIVES, THEIR PREPARATION AND INSECTICIDAL AND ACARICIDAL COMPOSITIONS CONTAINING THEM | SANKYO COMPANY LIMITED (JP) | 1986-11-12 | — | — | EP | disclosed |
| EP-0043035-B1 | PRESERVATIVE FOR WOOD AND WOODEN ARTICLES | Desowag-Bayer Holzschutz GmbH. (DE) | 1984-02-15 | — | — | EP | disclosed |
| EP-0043035-A1 | Preservative for wood and wooden articles | Desowag-Bayer Holzschutz GmbH. (DE) | 1982-01-06 | — | — | EP | disclosed |
| EP-0008606-B1 | AGENT FOR PRESERVING WOOD AND WOODEN MATERIAL | DEUTSCHE SOLVAY-WERKE GMBH (DE) | 1981-04-29 | — | — | EP | disclosed |
| JP-S5581802-A | REPELLENT WITH DURABILITY | IDEMITSU KOSAN CO LTD | 1980-06-20 | — | — | JP | disclosed |
| JP-S5581803-A | REPELLENT WITH DURABILITY | IDEMITSU KOSAN CO LTD | 1980-06-20 | — | — | JP | disclosed |
| EP-0008606-A1 | Agent for preserving wood and wooden material | DEUTSCHE SOLVAY-WERKE GMBH (DE) | 1980-03-19 | — | — | EP | disclosed |
| US-4035488-A | Insecticidal and acaricidal substituted phenyl thiophosphoric acid esters | CIBA-GEIGY CORPORATION (US) | 1977-07-12 | — | — | US | disclosed |
| US-3948940-A | Pesticidal phthalimido phosphorous ester compounds | CIBA-GEIGY CORPORATION (US) | 1976-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131085-A1 | CYTOCHROME P450 OXIDASE INHIBITORS AND USES THEREOF | CYP3A43, CYP3A5, POR | NPC1 913/4885RAB9A 4006/4885PAX8 4857/4885 |
| US-20140243340-A1 | CYTOCHROME P450 OXIDASE INHIBITORS AND USES THEREOF | CYP3A43, CYP3A5, POR | NPC1 913/4885RAB9A 4006/4885PAX8 4857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.