Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.45 |
| ▸ | FEN1 | P39748 | 1/20 | 0.45 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.42 |
| ▸ | TNKS | O95271 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8569494 | 0.83 | MEN1 (0.56) | KDM4EMEN1KMT2ASMN1; SMN2ERCC1 | |
| SCHEMBL30641227 | 0.82 | KDM4E (0.55) | KDM4EMEN1KMT2ASMN1; SMN2ERCC1 | |
| SCHEMBL26674806 | 0.82 | KDM4E (0.55) | KDM4EMEN1KMT2ASMN1; SMN2ERCC1 | |
| SCHEMBL6079815 | 0.79 | CA12 (0.45) | KDM4EMEN1KMT2AERCC1FEN1 | |
| SCHEMBL28342069 | 0.79 | KDM4E (0.54) | KDM4EMEN1KMT2ASMN1; SMN2STAT3 | |
| SCHEMBL23440107 | 0.78 | KDM4E (0.46) | KDM4EMEN1KMT2ASMN1; SMN2ERCC1 | |
| SCHEMBL29966763 | 0.78 | KDM4E (0.46) | KDM4EMEN1KMT2ASMN1; SMN2ERCC1 | |
| SCHEMBL29866310 | 0.78 | KDM4E (0.46) | KDM4EMEN1KMT2ASMN1; SMN2ERCC1 | |
| SCHEMBL30617298 | 0.78 | KDM4E (0.42) | KDM4EMEN1KMT2ASMN1; SMN2STAT3 | |
| SCHEMBL6080471 | 0.77 | ALDH1A1 (0.40) | KDM4EMEN1KMT2ASMN1; SMN2ERCC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060183909-A1 | Compositions derived from quinoline and quinoxaline, preparation and use thereof | NEURO3D (FR) | 2006-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183909-A1 | Compositions derived from quinoline and quinoxaline, preparation and use thereof | NQO1, NQO2, RECQL | KDM4E 1006/4885MEN1 740/4885KMT2A 1384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.