SCHEMBL6079906

SCHEMBL6079906

COc1cc(F)c2ncc(Cl)c(CCN3CC[C@H](N)[C@H](O)C3)c2c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 4/20 0.55
TRPC6 Q9Y210 1/20 0.38
CIT O14578 1/20 0.36
CHEK1 O14757 1/20 0.36
GAK O14976 1/20 0.36
STK10 O94804 1/20 0.36
PRKD3 O94806 1/20 0.36
ABL1 P00519 1/20 0.36
EGFR P00533 1/20 0.36
LCK P06239 1/20 0.36
FYN P06241 1/20 0.36
YES1 P07947 1/20 0.36
LYN P07948 1/20 0.36
RET P07949 1/20 0.36
HCK P08631 1/20 0.36
SRC P12931 1/20 0.36
PHKG2 P15735 1/20 0.36
PRKCA P17252 1/20 0.36
PRKACA P17612 1/20 0.36
CSNK2A2 P19784 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5745036 1.00 SLC2A1 (0.55) SLC2A1TRPC6CITCHEK1GAK
SCHEMBL6079813 1.00 SLC2A1 (0.55) SLC2A1TRPC6CITCHEK1GAK
SCHEMBL6079872 0.90 SLC2A1 (0.56) SLC2A1TRPC6KCNH2PDE10A
SCHEMBL6079870 0.90 SLC2A1 (0.56) SLC2A1TRPC6KCNH2PDE10A
SCHEMBL6079876 0.90 SLC2A1 (0.56) SLC2A1TRPC6KCNH2PDE10A
SCHEMBL6080909 0.87 SLC2A1 (0.62) SLC2A1TRPC6KCNH2PDE10A
SCHEMBL6079343 0.85 SLC2A1 (0.53) SLC2A1KCNH2CDK4CCND1CCND3
SCHEMBL6079796 0.85 SLC2A1 (0.53) SLC2A1KCNH2CDK4CCND1CCND3
SCHEMBL6079334 0.85 SLC2A1 (0.53) SLC2A1KCNH2CDK4CCND1CCND3
SCHEMBL6079786 0.85 SLC2A1 (0.53) SLC2A1KCNH2CDK4CCND1CCND3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060041123-A1 Antibacterial agents GLAXO GROUP LIMITED (GB) 2006-02-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060041123-A1 Antibacterial agents NQO2, NRDC, IFNG SLC2A1 4409/4885TRPC6 3722/4885CIT 2724/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.