Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KDM4A | O75164 | 9/20 | 0.45 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8441732 | 0.76 | KDM4E (0.59) | KDM4EKMT2AKDM4AMAPTRAB9A | |
| SCHEMBL6080120 | 0.75 | TYR (0.42) | KDM4EKMT2ATYRMAPTRAB9A | |
| SCHEMBL16228292 | 0.73 | KDM4E (0.64) | KDM4EKMT2AKDM4AMAPTRAB9A | |
| SCHEMBL6080627 | 0.73 | MMP2 (0.53) | KDM4EKMT2AKDM4AMAPTRAB9A | |
| SCHEMBL6080448 | 0.72 | TYR (0.43) | KDM4EKMT2ATYRTDP1MGAM | |
| SCHEMBL16228318 | 0.70 | KDM4E (0.53) | KDM4EKMT2AKDM4AMAPTRAB9A | |
| SCHEMBL6079800 | 0.70 | KDM4E (0.53) | KDM4EKMT2AKDM4AMAPTRAB9A | |
| SCHEMBL4309921 | 0.69 | KDM4E (0.49) | KDM4EKMT2AKDM4AMAPTRAB9A | |
| SCHEMBL27591912 | 0.69 | KDM4E (0.51) | KDM4EKMT2AKDM4AMAPTRAB9A | |
| SCHEMBL6080177 | 0.69 | KDM4E (0.58) | KDM4EKMT2AKDM4AMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060183909-A1 | Compositions derived from quinoline and quinoxaline, preparation and use thereof | NEURO3D (FR) | 2006-08-17 | — | — | US | claimed |
| US-20060183909-A1 | Compositions derived from quinoline and quinoxaline, preparation and use thereof | NEURO3D (FR) | 2006-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183909-A1 | Compositions derived from quinoline and quinoxaline, preparation and use thereof | NQO1, NQO2, RECQL | KDM4E 1006/4885KMT2A 1384/4885KDM4A 849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.