Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4364508 | 0.88 | GNRHR (0.72) | GNRHR | |
| SCHEMBL4367482 | 0.84 | GNRHR (0.65) | GNRHRCYP3A4 | |
| SCHEMBL4375095 | 0.84 | GNRHR (0.65) | GNRHRCYP3A4 | |
| SCHEMBL13812078 | 0.81 | GNRHR (0.55) | GNRHRCYP3A4 | |
| SCHEMBL13821600 | 0.81 | GNRHR (0.63) | GNRHRCYP3A4 | |
| SCHEMBL13812079 | 0.79 | GNRHR (0.66) | GNRHRCYP3A4 | |
| SCHEMBL13812037 | 0.78 | GNRHR (0.65) | GNRHRCYP3A4 | |
| SCHEMBL4367855 | 0.77 | GNRHR (0.73) | GNRHRCYP3A4 | |
| SCHEMBL13812048 | 0.77 | GNRHR (0.62) | GNRHRCYP3A4 | |
| SCHEMBL13812086 | 0.76 | GNRHR (0.77) | GNRHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7132442-B2 | 6H-thieno[2, 3-b]pyrrole derivatives as antagonists of gonadotropin releasing hormone (GnRH) | ASTRAZENECA AB (SE) | 2006-11-07 | — | — | US | disclosed |
| US-20060004082-A1 | 6H-thieno'2, 3-b!pyrrole derivatives as antagonists of gonadotropin releasing hormone (gnrh) | ASTRAZENECA (SE) | 2006-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060004082-A1 | 6H-thieno'2, 3-b!pyrrole derivatives as antagonists of gonadotropin releasing hormone (gnrh) | GNRHR, PRLHR, GHRHR | GNRHR 1/4885CYP3A4 1927/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.