Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 3/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3983979 | 0.82 | CA1 (0.55) | P2RX4P2RX7RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL15160055 | 0.79 | P2RX4 (0.49) | P2RX4P2RX7RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6588122 | 0.76 | P2RX4 (0.45) | P2RX4P2RX7RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6588125 | 0.76 | P2RX4 (0.45) | P2RX4P2RX7RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4826296 | 0.76 | P2RX4 (0.49) | P2RX4P2RX7RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL17027092 | 0.75 | P2RX4 (0.51) | P2RX4P2RX7RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL13516845 | 0.75 | P2RX4 (0.48) | P2RX4P2RX7RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL17027052 | 0.74 | P2RX4 (0.50) | P2RX4P2RX7RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL5391295 | 0.74 | ALDH1A1 (0.49) | P2RX4P2RX7RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4821297 | 0.71 | CYP1A2 (0.55) | P2RX4P2RX7RAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060183909-A1 | Compositions derived from quinoline and quinoxaline, preparation and use thereof | NEURO3D (FR) | 2006-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183909-A1 | Compositions derived from quinoline and quinoxaline, preparation and use thereof | NQO1, NQO2, RECQL | P2RX4 322/4885P2RX7 112/4885RAB9A 431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.