Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | BID | P55957 | 7/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 7/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 6/20 | 0.41 |
| ▸ | BAK1 | Q16611 | 6/20 | 0.41 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6080167 | 0.95 | KDM4E (0.48) | KDM4EKMT2ABIDMCL1BCL2L1 | |
| SCHEMBL6080305 | 0.88 | BID (0.56) | KDM4EKMT2ABIDMCL1BCL2L1 | |
| SCHEMBL6080099 | 0.85 | KDM4E (0.47) | KDM4EKMT2ABIDMCL1BCL2L1 | |
| Hydrochloric Acid SCHEMBL6080927 | 0.84 | KDM4E (0.46) | KDM4EKMT2ABIDMCL1BCL2L1 | |
| SCHEMBL6079288 | 0.81 | KDM4E (0.51) | KDM4EKMT2ABIDMCL1BCL2L1 | |
| SCHEMBL6080554 | 0.81 | CYP4A11 (0.40) | KDM4EKMT2AMEN1MAPTLMNA | |
| SCHEMBL6079612 | 0.81 | CYP4A11 (0.40) | KDM4EKMT2AMEN1MAPTLMNA | |
| SCHEMBL6605390 | 0.80 | FDPS (0.38) | KDM4EKMT2ATSHRIGFBP5MMP2 | |
| Hydrochloric Acid SCHEMBL6080849 | 0.79 | FDPS (0.37) | KDM4EKMT2ATSHRIGFBP5MMP2 | |
| SCHEMBL6599193 | 0.79 | HDAC3 (0.45) | MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060183909-A1 | Compositions derived from quinoline and quinoxaline, preparation and use thereof | NEURO3D (FR) | 2006-08-17 | — | — | US | claimed |
| US-20060183909-A1 | Compositions derived from quinoline and quinoxaline, preparation and use thereof | NEURO3D (FR) | 2006-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183909-A1 | Compositions derived from quinoline and quinoxaline, preparation and use thereof | NQO1, NQO2, RECQL | KDM4E 1006/4885KMT2A 1384/4885BID 2995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.