SCHEMBL6080508

SCHEMBL6080508

O=C(O)N[C@@H]1CCN(CCc2c(Cl)cnc3ccc(F)cc23)C[C@H]1O

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 1/20 0.40
KCNH2 Q12809 7/20 0.39
IDO1 P14902 4/20 0.37
TDO2 P48775 4/20 0.37
CYP2C8 P10632 1/20 0.37
CNR2 P34972 1/20 0.36
MALT1 Q9UDY8 1/20 0.35
MAPT P10636 1/20 0.35
CDK4 P11802 1/20 0.35
CCND1 P24385 1/20 0.35
CCND3 P30281 1/20 0.35
CDK6 Q00534 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6080502 1.00 SLC2A1 (0.40) SLC2A1KCNH2IDO1TDO2CYP2C8
SCHEMBL6079976 0.91 SLC2A1 (0.38) SLC2A1KCNH2CNR2CDK4CCND1
SCHEMBL6079967 0.91 SLC2A1 (0.38) SLC2A1KCNH2CNR2CDK4CCND1
SCHEMBL6080763 0.86 CNR2 (0.44) SLC2A1KCNH2CNR2MAPT
SCHEMBL6079988 0.83 CYP19A1 (0.45) SLC2A1KCNH2IDO1TDO2CYP2C8
SCHEMBL6079343 0.79 SLC2A1 (0.53) SLC2A1KCNH2CDK4CCND1CCND3
SCHEMBL6079786 0.79 SLC2A1 (0.53) SLC2A1KCNH2CDK4CCND1CCND3
SCHEMBL6079334 0.79 SLC2A1 (0.53) SLC2A1KCNH2CDK4CCND1CCND3
SCHEMBL6079796 0.79 SLC2A1 (0.53) SLC2A1KCNH2CDK4CCND1CCND3
Hydrochloric Acid SCHEMBL5745609 0.78 KCNH2 (0.63) SLC2A1KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060041123-A1 Antibacterial agents GLAXO GROUP LIMITED (GB) 2006-02-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060041123-A1 Antibacterial agents NQO2, NRDC, IFNG SLC2A1 4409/4885KCNH2 3365/4885IDO1 2566/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.