Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IP6K1 | Q92551 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | NQO2 | P16083 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | S100B | P04271 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6080185 | 0.89 | KDM4E (0.40) | IP6K1KDM4ENQO2ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL6080316 | 0.84 | IP6K1 (0.44) | IP6K1KDM4ENPC1RAB9ANPSR1 | |
| SCHEMBL6080256 | 0.79 | NQO2 (0.45) | KDM4ENQO2ALDH1A1MAPTGAA | |
| SCHEMBL6079518 | 0.79 | NQO2 (0.45) | KDM4ENQO2ALDH1A1MAPTGAA | |
| SCHEMBL6081104 | 0.77 | NQO2 (0.45) | KDM4ENQO2ALDH1A1MAPTGAA | |
| SCHEMBL21044498 | 0.77 | RAB9A (0.43) | KDM4ENPC1SMN1; SMN2RAB9ANPSR1 | |
| SCHEMBL6080021 | 0.76 | NQO2 (0.49) | KDM4ENPC1SMN1; SMN2RAB9ANQO2 | |
| SCHEMBL6079733 | 0.76 | NQO2 (0.43) | KDM4ENQO2ALDH1A1MAPTGAA | |
| SCHEMBL6079506 | 0.76 | KDM4E (0.53) | KDM4ENPC1SMN1; SMN2RAB9ANPSR1 | |
| SCHEMBL6080010 | 0.74 | KDM4E (0.51) | KDM4ENPC1SMN1; SMN2RAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060183909-A1 | Compositions derived from quinoline and quinoxaline, preparation and use thereof | NEURO3D (FR) | 2006-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183909-A1 | Compositions derived from quinoline and quinoxaline, preparation and use thereof | NQO1, NQO2, RECQL | IP6K1 2909/4885KDM4E 1006/4885NPC1 1911/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.