Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3867013 | 0.80 | MEN1 (0.42) | MEN1KMT2A | |
| SCHEMBL6081285 | 0.77 | MEN1 (0.30) | MEN1KMT2A | |
| SCHEMBL27810381 | 0.72 | TSHR (0.34) | MEN1KMT2A | |
| SCHEMBL17617159 | 0.69 | TSHR (0.32) | MEN1KMT2A | |
| SCHEMBL27889909 | 0.67 | — | — | |
| SCHEMBL28441433 | 0.66 | TSHR (0.36) | MEN1KMT2A | |
| SCHEMBL28622784 | 0.66 | LMNA (0.35) | MEN1KMT2A | |
| SCHEMBL127989 | 0.65 | TSHR (0.39) | MEN1KMT2APTPN1 | |
| SCHEMBL27810382 | 0.65 | TSHR (0.39) | MEN1KMT2A | |
| SCHEMBL17617226 | 0.65 | LMNA (0.31) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060079503-A1 | Thiazolidinones and the use therof as polo-like kinase inhibitors | SCHERING AKTIENGESELLSCHAFT | 2006-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060079503-A1 | Thiazolidinones and the use therof as polo-like kinase inhibitors | PLK4, PLK2, PLK3 | MEN1 3800/4885KMT2A 3723/4885PTPN1 2122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.