⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15402748 | 1.00 | — | — | |
| SCHEMBL5175306 | 0.92 | — | — | |
| SCHEMBL6937961 | 0.90 | MAPT (0.45) | — | |
| SCHEMBL2008821 | 0.90 | MAPT (0.45) | — | |
| SCHEMBL154894 | 0.90 | MAPT (0.45) | — | |
| SCHEMBL477776 | 0.82 | — | — | |
| SCHEMBL477980 | 0.82 | — | — | |
| SCHEMBL478076 | 0.82 | — | — | |
| SCHEMBL14571190 | 0.82 | DNM1 (0.45) | — | |
| SCHEMBL5683390 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0469893-B1 | Fluorinated pyrimidine-phenyl optically active compounds and liquid crystal compositions thereof | TAKASAGO PERFUMERY CO LTD (JP) | 1995-12-13 | — | — | EP | claimed |
| CN-101128469-B | Protease inhibitor precursor synthesis | TIBOTEC PHARM LTD | 2012-11-14 | — | — | CN | disclosed |
| US-8183394-B2 | Protease inhibitor precursor synthesis | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2012-05-22 | — | — | US | disclosed |
| US-20120041215-A1 | PROTEASE INHIBITOR PRECURSOR SYNTHESIS | JANSSEN SCIENCES IRELAND UC (IE) | 2012-02-16 | — | — | US | disclosed |
| US-8067463-B2 | Protease inhibitor precursor synthesis | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2011-11-29 | — | — | US | disclosed |
| EP-1856125-B1 | PROTEASE INHIBITOR PRECURSOR SYNTHESIS | TIBOTEC PHARM LTD (IE) | 2009-08-26 | — | — | EP | disclosed |
| US-20090054668-A1 | Protease inhibitor precursor synthesis | JANSSEN SCIENCES IRELAND UC (IE) | 2009-02-26 | — | — | US | disclosed |
| CN-101128469-A | Protease inhibitor precursor synthesis | TIBOTEC PHARM LTD (IE) | 2008-02-20 | — | — | CN | disclosed |
| EP-1856125-A1 | PROTEASE INHIBITOR PRECURSOR SYNTHESIS | Tibotec Pharmaceuticals Ltd. (IE) | 2007-11-21 | — | — | EP | disclosed |
| WO-2006089942-A1 | PROTEASE INHIBITOR PRECURSOR SYNTHESIS | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2006-08-31 | — | — | WO | disclosed |
| EP-0687678-A1 | Cyclohexanone compounds, process for preparing the same, and processes for preparing silacyclohexane-based liquid crystal compounds from the cyclohexanone compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1995-12-20 | — | — | EP | disclosed |
| EP-0676402-A1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-10-11 | — | — | EP | disclosed |
| EP-0670322-A1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-09-06 | — | — | EP | disclosed |
| EP-0668285-A1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-08-23 | — | — | EP | disclosed |
| EP-0668284-A1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-08-23 | — | — | EP | disclosed |
| EP-0668286-A1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-08-23 | — | — | EP | disclosed |
| EP-0665232-A1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-08-02 | — | — | EP | disclosed |
| EP-0659753-A1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-06-28 | — | — | EP | disclosed |
| EP-0657460-A1 | A silacyclohexane compound, a method of prepraring it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1995-06-14 | — | — | EP | disclosed |
| EP-0650969-A1 | A Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-05-03 | — | — | EP | disclosed |