SCHEMBL608166

SCHEMBL608166

O=C(/C=C/C(=O)OCCO)OCCO

nearest known ligand 0.64

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.64
ATM Q13315 1/20 0.54
HCAR2 Q8TDS4 7/20 0.50
MAPT P10636 1/20 0.39
RAB9A P51151 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
ALDH1A1 P00352 3/20 0.39
TP53 P04637 2/20 0.39
HIF1A Q16665 2/20 0.39
CYP3A4 P08684 1/20 0.39
HSD17B10 Q99714 1/20 0.39
KEAP1 Q14145 1/20 0.36
NFE2L2 Q16236 1/20 0.36
APP P05067 2/20 0.36
ESR1 P03372 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL216328 1.00 TSHR (0.64) TSHRATMHCAR2MAPTRAB9A
SCHEMBL1455147 1.00 TSHR (0.64) TSHRATMHCAR2MAPTRAB9A
Ammonia Solution, Strong SCHEMBL16950024 0.97 TSHR (0.61) TSHRATMHCAR2MAPTRAB9A
SCHEMBL28233064 0.97 TSHR (0.61) TSHRATMHCAR2MAPTRAB9A
SCHEMBL26125596 0.90 TSHR (0.54) TSHRATMHCAR2MAPTRAB9A
SCHEMBL216329 0.90 HCAR2 (0.65) TSHRATMHCAR2MAPTRAB9A
SCHEMBL608165 0.90 HCAR2 (0.65) TSHRATMHCAR2MAPTRAB9A
SCHEMBL216330 0.90 HCAR2 (0.65) TSHRATMHCAR2MAPTRAB9A
SCHEMBL822395 0.89 TSHR (0.58) TSHRATMHCAR2MAPTRAB9A
SCHEMBL10672946 0.88 TSHR (0.52) TSHRATMHCAR2MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 743 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117079959-B Magnetic nano material for detecting glycoprotein and preparation method thereof 四川赛尔医学检验有限公司 2024-03-22 CN claimed
CN-117079959-A Magnetic nano material for detecting glycoprotein and preparation method thereof 四川赛尔医学检验有限公司 2023-11-17 CN claimed
CN-116234898-A Notch signaling inhibitors for the treatment of obesity and metabolic disorders 普渡研究基金会 2023-06-06 CN claimed
CN-114805855-B Bioactive hydrogel with controllable charges and preparation method and application thereof 华中科技大学同济医学院附属同济医院 2023-03-10 CN claimed
CN-114929859-A Biological material for preventing and treating tissue lesions 诺瓦迪普生物科学股份公司 2022-08-19 CN claimed
CN-114805855-A Bioactive hydrogel with controllable charge and preparation method and application thereof 华中科技大学同济医学院附属同济医院 2022-07-29 CN claimed
EP-3996842-A1 MULTI-WELL PLATE AND METHOD FOR PREPARING SAME Centre national de la recherche scientifique (FR) 2022-05-18 EP claimed
US-20220081555-A1 COMPOSITION INCLUDING POLYESTER RESIN AND VINYL ESTER AND METHOD OF USING THE SAME 3M INNOVATIVE PROPERTIES COMPANY 2022-03-17 US claimed
CN-110563933-B Preparation method of ultrahigh molecular weight PBS 宁波窦氏化学科技有限公司 2022-03-11 CN claimed
EP-3898815-A1 COMPOSITION INCLUDING POLYESTER RESIN AND VINYL ESTER AND METHOD OF USING THE SAME 3M Innovative Properties Company (US) 2021-10-27 EP claimed
US-6040350-A Epoxy resin type composition for stiffening vehicle body and method for stiffening vehicle body NISSAN MOTOR CO., LTD. (JP) 2000-03-21 US claimed
US-5847046-A Biodegradable bone cement UNITED STATES SURGICAL CORPORATION (US) 1998-12-08 US claimed
EP-0425436-B1 Reactive silicone and/or fluorine containing hydrophilic prepolymers and polymers thereof CIBA GEIGY AG (CH) 1996-12-27 EP claimed
EP-0276492-B1 Silicone-based stabilizers useful in the preparation of improved polyurethane foams UNION CARBIDE CORP (US) 1994-06-01 EP claimed
EP-0425436-A2 Reactive silicone and/or fluorine containing hydrophilic prepolymers and polymers thereof CIBA-GEIGY AG (CH) 1991-05-02 EP claimed
US-4212790-A Resin concrete composition ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1980-07-15 US claimed
US-4152308-A SILICEOUS FILLED VULCANIZATES POLYSAR LIMITED (CA) 1979-05-01 US claimed
US-4150014-A HYDROXYL HYDROCARBYL POLYMER, AMINE, SHEARING POLYSAR LIMITED (CA) 1979-04-17 US claimed
US-4150015-A MONOAZO OR AZO-METHINE DYES REACTED WITH A 2-(CYCLOPENTAN-1-ON-2-YLIDENE)CHROMAN COMPOUND POLYSAR LIMITED (CA) 1979-04-17 US claimed
US-3941912-A Copolymer latex and paper coating composition thereof SUMITOMO NAUGATUCK CO., LTD. (JA) 1976-03-02 US claimed