SCHEMBL1455147

SCHEMBL1455147

O=C(C=CC(=O)OCCO)OCCO

nearest known ligand 0.64

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.64
ATM Q13315 1/20 0.54
HCAR2 Q8TDS4 7/20 0.50
MAPT P10636 1/20 0.39
RAB9A P51151 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
ALDH1A1 P00352 3/20 0.39
TP53 P04637 2/20 0.39
HIF1A Q16665 2/20 0.39
CYP3A4 P08684 1/20 0.39
HSD17B10 Q99714 1/20 0.39
KEAP1 Q14145 1/20 0.36
NFE2L2 Q16236 1/20 0.36
APP P05067 2/20 0.36
ESR1 P03372 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL608166 1.00 TSHR (0.64) TSHRATMHCAR2MAPTRAB9A
SCHEMBL216328 1.00 TSHR (0.64) TSHRATMHCAR2MAPTRAB9A
Ammonia Solution, Strong SCHEMBL16950024 0.97 TSHR (0.61) TSHRATMHCAR2MAPTRAB9A
SCHEMBL28233064 0.97 TSHR (0.61) TSHRATMHCAR2MAPTRAB9A
SCHEMBL26125596 0.90 TSHR (0.54) TSHRATMHCAR2MAPTRAB9A
SCHEMBL216329 0.90 HCAR2 (0.65) TSHRATMHCAR2MAPTRAB9A
SCHEMBL608165 0.90 HCAR2 (0.65) TSHRATMHCAR2MAPTRAB9A
SCHEMBL216330 0.90 HCAR2 (0.65) TSHRATMHCAR2MAPTRAB9A
SCHEMBL822395 0.89 TSHR (0.58) TSHRATMHCAR2MAPTRAB9A
SCHEMBL10672946 0.88 TSHR (0.52) TSHRATMHCAR2MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 374 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119307207-A Negative electrode binder, negative electrode plate and electrochemical energy storage device 峻益天材(深圳)新能源有限公司 2025-01-14 CN claimed
US-7964696-B2 Chain extenders POLYNOVO BIOMATERIALS PTY LIMITED (AU) 2011-06-21 US claimed
US-20090175921-A1 Chain Extenders POLYNOVO BIOMATERIALS PTY LIMITED 2009-07-09 US claimed
EP-1945690-A1 CHAIN EXTENDERS Polynovo Biomaterials Pty Limited (AU) 2008-07-23 EP claimed
WO-2007033418-A1 CHAIN EXTENDERS POLYNOVO BIOMATERIALS PTY LIMITED (AU) 2007-03-29 WO claimed
US-6512053-B1 Employed in manufacturing tire tread formulations that have rolling resistance and treadwear characteristics that are similar to those made with solution SBR but with improved traction characteristics. THE GOODYEAR TIRE & RUBBER COMPANY 2003-01-28 US claimed
US-6455655-B1 FOR TIRE TREADS; ROLLING RESISTANCE, TREADWEAR, WITH IMPROVED TRACTION; THE RUBBER INCLUDES HYDROXYALKYL ACRYLATE MONOMER, AND HAS SPECIFIED LIGHT SCATTERING TO REFRACTIVE INDEX RATIO THE GOODYEAR TIRE & RUBBER COMPANY 2002-09-24 US claimed
US-20020061955-A1 Emulsion styrene-butadiene rubber GOODYEAR TIRE & RUBBER COMPANY, THE 2002-05-23 US claimed
US-6111045-A YIELDS A VULCANIZED RUBBER SHOWING IMPROVEMENTS IN HEAT BUILD-UP, TENSILE STRENGTH, ABRASION RESISTANCE AND PROCESSABILITY NIPPON ZEON CO. LTD. (JP) 2000-08-29 US claimed
US-5874148-A Water resistant textile coating and method of using the same REICHHOLD CHEMICALS, INC. (US) 1999-02-23 US claimed
US-5079319-A Contact Lenses CIBA-GEIGY CORPORATION (US) 1992-01-07 US claimed
EP-0425436-A2 Reactive silicone and/or fluorine containing hydrophilic prepolymers and polymers thereof CIBA-GEIGY AG (CH) 1991-05-02 EP claimed
US-4950711-A CONJUGATED DIENE, MONOOLEFIN, AND UNSATURATED CARBOXYLIC ACID MONOMERS REICHHOLD CHEMICALS, INC. (US) 1990-08-21 US claimed
US-4707513-A CROSSLINKED ELASTOMER CORE MONSANTO COMPANY (US) 1987-11-17 US claimed
US-4617343-A ACRYLIC RESINS INCLUDING SULFO UNSATURATED MONOMERS; ALCOHOL-DILUTABLE; NONSMEARING OF PRINTER SURFACES NATIONAL STARCH AND CHEMICAL CORPORATION (US) 1986-10-14 US claimed
US-4259460-A BLENDS OF POLYMERS OF VINYL CHLORIDE, ACRYLONITRILE-BUTADIENE, AND BUTADIENE-STYRENE-TERTIARY AMINE POLYSAR LIMITED (CA) 1981-03-31 US claimed
US-4152308-A SILICEOUS FILLED VULCANIZATES POLYSAR LIMITED (CA) 1979-05-01 US claimed
US-4150015-A MONOAZO OR AZO-METHINE DYES REACTED WITH A 2-(CYCLOPENTAN-1-ON-2-YLIDENE)CHROMAN COMPOUND POLYSAR LIMITED (CA) 1979-04-17 US claimed
US-4150014-A HYDROXYL HYDROCARBYL POLYMER, AMINE, SHEARING POLYSAR LIMITED (CA) 1979-04-17 US claimed
US-3941912-A Copolymer latex and paper coating composition thereof SUMITOMO NAUGATUCK CO., LTD. (JA) 1976-03-02 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090175921-A1 Chain Extenders UMPS, PUF60, SMC1A TSHR 3975/4885ATM 3246/4885HCAR2 2351/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.