Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.30 |
| ▸ | CDC25B | P30305 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4826218 | 0.78 | ACACB (0.41) | MEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL3998006 | 0.78 | MEN1 (0.42) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL6083518 | 0.74 | — | — | |
| SCHEMBL598576 | 0.73 | MEN1 (0.45) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL81885 | 0.70 | ALDH1A1 (0.50) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL9638982 | 0.70 | — | — | |
| SCHEMBL15302214 | 0.69 | MEN1 (0.42) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL8212898 | 0.69 | MEN1 (0.47) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL21453077 | 0.69 | MEN1 (0.42) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL18723208 | 0.69 | MEN1 (0.42) | MEN1CYP3A4ALOX15KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7071359-B1 | Neuropathy improvers containing nitrogenous compounds as the active ingredient | TEIJIN LIMITED (JP) | 2006-07-04 | — | — | US | disclosed |
| EP-1201235-B1 | NEUROPATHY IMPROVERS CONTAINING NITROGENOUS COMPOUNDS AS THE ACTIVE INGREDIENT | TEIJIN LTD (JP) | 2005-10-12 | — | — | EP | disclosed |
| EP-1201235-A1 | NEUROPATHY IMPROVERS CONTAINING NITROGENOUS COMPOUNDS AS THE ACTIVE INGREDIENT | TEIJIN LIMITED (JP) | 2002-05-02 | — | — | EP | disclosed |