Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.43 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 3/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1266499 | 0.83 | MAPT (0.61) | MAPTGPR84FFAR1LMNALCK | |
| SCHEMBL8694164 | 0.79 | MAPT (1.00) | MAPTGPR84FFAR1LCKPPARD | |
| SCHEMBL338043 | 0.79 | MAPT (1.00) | MAPTGPR84FFAR1LCKPPARD | |
| SCHEMBL9292097 | 0.79 | MAPT (1.00) | MAPTGPR84FFAR1LCKPPARD | |
| SCHEMBL337879 | 0.79 | MAPT (1.00) | MAPTGPR84FFAR1LCKPPARD | |
| SCHEMBL7461276 | 0.79 | MAPT (1.00) | MAPTGPR84FFAR1LCKPPARD | |
| SCHEMBL9291062 | 0.79 | MAPT (1.00) | MAPTGPR84FFAR1LCKPPARD | |
| SCHEMBL337289 | 0.79 | MAPT (1.00) | MAPTGPR84FFAR1LCKPPARD | |
| SCHEMBL21808105 | 0.79 | MAPT (1.00) | MAPTGPR84FFAR1LCKPPARD | |
| SCHEMBL337512 | 0.79 | MAPT (1.00) | MAPTGPR84FFAR1LCKPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7071359-B1 | Neuropathy improvers containing nitrogenous compounds as the active ingredient | TEIJIN LIMITED (JP) | 2006-07-04 | — | — | US | disclosed |
| EP-1201235-B1 | NEUROPATHY IMPROVERS CONTAINING NITROGENOUS COMPOUNDS AS THE ACTIVE INGREDIENT | TEIJIN LTD (JP) | 2005-10-12 | — | — | EP | disclosed |
| CN-1377263-A | Neuropathy improves containing nitrogenous compounds as the active ingredient | TEIJIN LTD (JP) | 2002-10-30 | — | — | CN | disclosed |
| EP-1201235-A1 | NEUROPATHY IMPROVERS CONTAINING NITROGENOUS COMPOUNDS AS THE ACTIVE INGREDIENT | TEIJIN LIMITED (JP) | 2002-05-02 | — | — | EP | disclosed |