⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8862001 | 0.81 | PTGS1 (0.60) | — | |
| Formic Acid SCHEMBL26965059 | 0.79 | TP53 (0.54) | — | |
| SCHEMBL1795130 | 0.79 | PTGS1 (0.69) | — | |
| SCHEMBL21847980 | 0.79 | PTGS1 (0.69) | — | |
| SCHEMBL3302772 | 0.79 | TP53 (0.65) | — | |
| SCHEMBL1795132 | 0.79 | PTGS1 (0.69) | — | |
| SCHEMBL1005454 | 0.77 | — | — | |
| SCHEMBL30268861 | 0.76 | TP53 (0.56) | — | |
| SCHEMBL27567537 | 0.76 | TP53 (0.56) | — | |
| SCHEMBL23457950 | 0.75 | TP53 (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |
| US-7071359-B1 | Neuropathy improvers containing nitrogenous compounds as the active ingredient | TEIJIN LIMITED (JP) | 2006-07-04 | — | — | US | disclosed |
| EP-1201235-B1 | NEUROPATHY IMPROVERS CONTAINING NITROGENOUS COMPOUNDS AS THE ACTIVE INGREDIENT | TEIJIN LTD (JP) | 2005-10-12 | — | — | EP | disclosed |
| CN-1500086-A | Aminopiperidine derivatives | 霍夫曼-拉罗奇有限公司 | 2004-05-26 | — | — | CN | disclosed |
| EP-1417202-A2 | AMINOPIPERIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | F. HOFFMANN-LA ROCHE AG (CH) | 2004-05-12 | — | — | EP | disclosed |
| US-20030069276-A1 | Amino piperidine derivatives | F.HOFFMANN-LA ROCHE AG (CH) | 2003-04-10 | — | — | US | disclosed |
| EP-0993458-B1 | 3-BENZYLPIPERIDINE | MERCK PATENT GMBH (DE) | 2003-04-09 | — | — | EP | disclosed |
| WO-2002079186-A2 | AMINOPIPERIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | F. HOFFMANN-LA ROCHE AG (CH) | 2002-10-10 | — | — | WO | disclosed |
| EP-1201235-A1 | NEUROPATHY IMPROVERS CONTAINING NITROGENOUS COMPOUNDS AS THE ACTIVE INGREDIENT | TEIJIN LIMITED (JP) | 2002-05-02 | — | — | EP | disclosed |
| US-6333339-B1 | CENTRAL SYSTEM DISORDERS, SCHIZOPHRENIA AND COGNITION ACTIVATORS | MERCK PATENT GELLSCHAFT MIT BESCHRANKTER (DE) | 2001-12-25 | — | — | US | disclosed |
| WO-1998057953-A1 | 3-BENZYLPIPERIDINE | MERCK PATENT GMBH (DE) | 1998-12-23 | — | — | WO | disclosed |
| EP-0071126-B1 | PROCESS FOR THE MANUFACTURE OF ALDEHYDES | BAYER AG (DE) | 1984-09-12 | — | — | EP | disclosed |
| US-4420435-A | Alpha-hydroxy-phosphonic acid esters | BAYER AKTIENGESELLSCHAFT (DE) | 1983-12-13 | — | — | US | disclosed |
| EP-0031915-B1 | PROCESS FOR THE PRODUCTION OF HALOALKENES | BAYER AG (DE) | 1983-05-25 | — | — | EP | disclosed |
| EP-0071126-A1 | Process for the manufacture of aldehydes | BAYER AG (DE) | 1983-02-09 | — | — | EP | disclosed |
| US-4358409-A | Preparation of styryl cyclopropane insecticide intermediates | BAYER AKTIENGESELLSCHAFT (DE) | 1982-11-09 | — | — | US | disclosed |
| EP-0019719-B1 | PROCESS FOR PREPARING ALKENES, NOVEL INTERMEDIATES FOR THEIR PREPARATION AND PROCESS FOR PREPARING THEM | BAYER AG (DE) | 1982-07-21 | — | — | EP | disclosed |
| US-4330482-A | Process for the preparation of halogenoalkenes | BAYER AKTIENGESELLSCHAFT (DE) | 1982-05-18 | — | — | US | disclosed |
| EP-0031915-A1 | Process for the production of haloalkenes | BAYER AG (DE) | 1981-07-15 | — | — | EP | disclosed |
| EP-0019719-A1 | Process for preparing alkenes, novel intermediates for their preparation and process for preparing them | BAYER AG (DE) | 1980-12-10 | — | — | EP | disclosed |