SCHEMBL8862001

SCHEMBL8862001

Cc1cccc(C=CO)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 3/20 0.60
PTGS2 P35354 3/20 0.60
ALOX5 P09917 1/20 0.60
TDP1 Q9NUW8 2/20 0.56
TP53 P04637 1/20 0.56
NPC1 O15118 2/20 0.54
CASP3 P42574 1/20 0.54
SENP8 Q96LD8 1/20 0.54
SENP7 Q9BQF6 1/20 0.54
SENP6 Q9GZR1 1/20 0.54
RELA Q04206 1/20 0.53
FBP1 P09467 1/20 0.53
MAOA P21397 2/20 0.49
MAOB P27338 2/20 0.49
ACHE P22303 2/20 0.48
ALDH1A1 P00352 2/20 0.44
MAPK1 P28482 1/20 0.44
NFE2L2 Q16236 1/20 0.42
CYP1A2 P05177 1/20 0.42
MMP1 P03956 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1795130 0.85 PTGS1 (0.69) PTGS1PTGS2ALOX5TDP1TP53
SCHEMBL21847980 0.85 PTGS1 (0.69) PTGS1PTGS2ALOX5TDP1TP53
SCHEMBL1795132 0.85 PTGS1 (0.69) PTGS1PTGS2ALOX5TDP1TP53
SCHEMBL1179749 0.81 RELA (0.74) PTGS1PTGS2ALOX5TDP1TP53
SCHEMBL29862171 0.81 TP53 (0.60) PTGS1PTGS2ALOX5TDP1TP53
SCHEMBL23457950 0.81 TP53 (0.60) PTGS1PTGS2ALOX5TDP1TP53
SCHEMBL1179750 0.81 RELA (0.74) PTGS1PTGS2ALOX5TDP1TP53
SCHEMBL6083570 0.81
SCHEMBL29673932 0.81 RELA (0.74) PTGS1PTGS2ALOX5TDP1TP53
SCHEMBL18087628 0.79 TDP1 (0.53) PTGS1PTGS2ALOX5TDP1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5698369-A PHOTODECOMPOSABLE FUJI PHOTO FILM CO., LTD. (JP) 1997-12-16 US disclosed
EP-0417557-B1 Positive-working radiation-sensitive mixture and recording material prepared therefrom HOECHST AG (DE) 1996-12-11 EP disclosed
EP-0417556-B1 Positive-working radiation-sensitive mixture and recording material prepared therefrom HOECHST AG (DE) 1996-12-11 EP disclosed
EP-0444493-B1 Negative working radiation sensitive composition and radiation sensitive recording material produced therefrom HOECHST AG (DE) 1996-11-20 EP disclosed
EP-0456075-B1 Positive-working radiation-sensitive mixture and radiation-sensitive recording material for exposure using deep UV-radiation HOECHST AG (DE) 1996-09-11 EP disclosed
US-5424166-A Negative-working radiation-sensitive mixture containing diazomethane acid generator and a radiation-sensitive recording material produced therfrom HOECHST AKTIENGESELLSCHAFT (DE) 1995-06-13 US disclosed
EP-0378067-B1 Positively working radiation-sensitive mixture containing a multifunctional alpha-diazo-beta-keto ester, process for its preparation and a radiation-sensitive recording material containing this mixture HOECHST AG (DE) 1995-05-31 EP disclosed
US-5340682-A Sensitive, heat resistant, noncorrosive HOECHST AKTIENGESELLSCHAFT (DE) 1994-08-23 US disclosed
US-5338641-A Positive-working radiation-sensitive mixture and copying material produced therefrom comprising an α,α-bis(sulfonyl) diazo methane as an acid forming compound HOECHST AKTIENGESELLSCHAFT (DE) 1994-08-16 US disclosed
US-5256517-A Positive-working radiation-sensitive mixture and recording material for exposure to UV radiation containing polyfunctional compound having α-β-keto ester units and sulfonate units HOECHST AKTIENGESELLSCHAFT (DE) 1993-10-26 US disclosed
US-5198322-A Positively operating radiation-sensitive mixture containing a polyfunctional α-diazo-β-keto ester and radiation-sensitive recording material containing this mixture HOECHST AKTIENGESELLSCHAFT (DE) 1993-03-30 US disclosed
EP-0456075-A1 Positive-working radiation-sensitive mixture and radiation-sensitive recording material for exposure using deep UV-radiation HOECHST AKTIENGESELLSCHAFT (DE) 1991-11-13 EP disclosed
EP-0444493-A2 Negative working radiation sensitive composition and radiation sensitive recording material produced therefrom HOECHST AKTIENGESELLSCHAFT (DE) 1991-09-04 EP disclosed
EP-0417557-A2 Positive-working radiation-sensitive mixture and recording material prepared therefrom HOECHST AKTIENGESELLSCHAFT (DE) 1991-03-20 EP disclosed
EP-0417556-A2 Positive-working radiation-sensitive mixture and recording material prepared therefrom HOECHST AKTIENGESELLSCHAFT (DE) 1991-03-20 EP disclosed
EP-0378067-A2 Positively working radiation-sensitive mixture containing a multifunctional alpha-diazo-beta-keto ester, process for its preparation and a radiation-sensitive recording material containing this mixture HOECHST AKTIENGESELLSCHAFT (DE) 1990-07-18 EP disclosed