SCHEMBL608360

SCHEMBL608360

c1ccc(CN2CCN(CC3CO3)CC2)cc1

nearest known ligand 0.66

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 9/20 0.66
HTR1A P08908 2/20 0.66
TMEM97 Q5BJF2 3/20 0.59
ADRA2A P08913 1/20 0.58
ADRA2B P18089 1/20 0.58
ADRA2C P18825 1/20 0.58
ABCB1 P08183 1/20 0.56
MC4R P32245 1/20 0.55
DRD4 P21917 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL608348 0.83 MAPT (0.50) SIGMAR1HTR1ADRD4
SCHEMBL1041303 0.80 SIGMAR1 (1.00) SIGMAR1MC4RDRD4
SCHEMBL242970 0.80 SIGMAR1 (1.00) SIGMAR1MC4RDRD4
SCHEMBL8188324 0.80 SIGMAR1 (1.00) SIGMAR1MC4RDRD4
SCHEMBL1415730 0.80 SIGMAR1 (1.00) SIGMAR1MC4RDRD4
SCHEMBL576868 0.80 SIGMAR1 (1.00) SIGMAR1MC4RDRD4
SCHEMBL608681 0.80 SIGMAR1 (0.69) SIGMAR1
SCHEMBL2489199 0.80 SIGMAR1 (1.00) SIGMAR1MC4RDRD4
SCHEMBL3017719 0.79 SIGMAR1 (0.51) SIGMAR1HTR1ATMEM97ADRA2AADRA2B
SCHEMBL3017320 0.79 MC4R (0.55) SIGMAR1HTR1ATMEM97ADRA2AADRA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120025500-A Photopolymer holographic recording medium, preparation method and application thereof 珠海莫界科技有限公司 2025-05-23 CN claimed
CN-119889530-A Photopolymer holographic recording medium, volume hologram grating, optical waveguide, and apparatus 珠海莫界科技有限公司 2025-04-25 CN claimed
CN-119889529-A Photopolymer holographic recording medium, volume hologram grating, optical waveguide, and apparatus 珠海莫界科技有限公司 2025-04-25 CN claimed
CN-119798564-A Photopolymer holographic recording medium, grating, preparation method and equipment thereof 珠海莫界科技有限公司 2025-04-11 CN claimed
EP-1237887-B1 9-(PIPERAZINYLALKYL)CARBAZOLES AS BAX-MODULATORS SERONO LAB (CH) 2008-06-04 EP claimed
EP-1237887-A1 9-(PIPERAZINYLALKYL)CARBAZOLES AS BAX-MODULATORS Applied Research Systems ARS Holding N.V. (AN) 2002-09-11 EP claimed
WO-2001029028-A1 9- (PIPERAZINYLALKYL) CARBAZOLES AS BAX-MODULATORS APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) 2001-04-26 WO claimed
CN-120025500-A Photopolymer holographic recording medium, preparation method and application thereof 珠海莫界科技有限公司 2025-05-23 CN disclosed
CN-119889530-A Photopolymer holographic recording medium, volume hologram grating, optical waveguide, and apparatus 珠海莫界科技有限公司 2025-04-25 CN disclosed
CN-119889529-A Photopolymer holographic recording medium, volume hologram grating, optical waveguide, and apparatus 珠海莫界科技有限公司 2025-04-25 CN disclosed
CN-119798564-A Photopolymer holographic recording medium, grating, preparation method and equipment thereof 珠海莫界科技有限公司 2025-04-11 CN disclosed
CN-107743498-B Initiator for copolymerization of diene monomer and vinyl aromatic monomer 西索斯公司 2020-04-28 CN disclosed
US-10584187-B2 Initiators for the copolymerisation of diene monomers and vinyl aromatic monomers SYNTHOS S.A. (PL) 2020-03-10 US disclosed
US-20100099810-A1 POLYMER, RUBBER COMPOSITION AND TIRE USING THE SAME SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2010-04-22 US disclosed
US-20100099795-A1 RUBBER COMPOSITION AND TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2010-04-22 US disclosed
EP-2177562-A2 Polymer, rubber composition and tire using the same Sumitomo Rubber Industries, Ltd. (JP) 2010-04-21 EP disclosed
EP-1237887-B1 9-(PIPERAZINYLALKYL)CARBAZOLES AS BAX-MODULATORS SERONO LAB (CH) 2008-06-04 EP disclosed
EP-1237887-A1 9-(PIPERAZINYLALKYL)CARBAZOLES AS BAX-MODULATORS Applied Research Systems ARS Holding N.V. (AN) 2002-09-11 EP disclosed
WO-2001029028-A1 9- (PIPERAZINYLALKYL) CARBAZOLES AS BAX-MODULATORS APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) 2001-04-26 WO disclosed
EP-1094063-A1 9-(Piperazinylalkyl)carbazoles as Bax-modulators Applied Research Systems ARS Holding N.V. (AN) 2001-04-25 EP disclosed