SCHEMBL60843

SCHEMBL60843

N#CC(C#N)=Cc1ccccc1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.76
KMT2A Q03164 9/20 0.76
ALDH1A1 P00352 9/20 0.76
MEN1 O00255 8/20 0.76
KDM4E B2RXH2 6/20 0.76
LMNA P02545 4/20 0.76
NPSR1 Q6W5P4 3/20 0.76
POLB P06746 2/20 0.76
THRB P10828 1/20 0.64
CISD1 Q9NZ45 1/20 0.64
EGFR P00533 4/20 0.61
MAPK1 P28482 2/20 0.59
CYP3A4 P08684 3/20 0.55
HPGD P15428 3/20 0.55
TSHR P16473 3/20 0.55
NFKB1 P19838 3/20 0.55
BLM P54132 3/20 0.55
PMP22 Q01453 3/20 0.55
CYP1A2 P05177 3/20 0.55
APEX1 P27695 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28271363 0.98 MAPT (0.73) MAPTKMT2AALDH1A1MEN1KDM4E
SCHEMBL20824922 0.97 KMT2A (0.80) MAPTKMT2AALDH1A1MEN1KDM4E
SCHEMBL17466937 0.91 KMT2A (0.71) MAPTKMT2AALDH1A1MEN1KDM4E
SCHEMBL17466932 0.87 MAPT (1.00) MAPTKMT2AALDH1A1MEN1KDM4E
SCHEMBL17466930 0.87 MAPT (0.71) MAPTKMT2AALDH1A1MEN1KDM4E
SCHEMBL9985945 0.87 MAPT (0.58) MAPTKMT2AALDH1A1MEN1KDM4E
SCHEMBL953427 0.87 MAPT (0.58) MAPTKMT2AALDH1A1MEN1KDM4E
SCHEMBL5386096 0.87 MAPT (0.58) MAPTKMT2AALDH1A1MEN1KDM4E
SCHEMBL5386095 0.87 MAPT (0.58) MAPTKMT2AALDH1A1MEN1KDM4E
SCHEMBL18868872 0.83 MAPT (0.65) MAPTKMT2AALDH1A1MEN1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2700 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025095132-A1 POROUS RESIN BEAD, METHOD FOR PRODUCING SAME, AND METHOD FOR PRODUCING NUCLEIC ACID USING SAID POROUS RESIN BEAD 日東電工株式会社 2025-05-08 WO claimed
CN-119221275-B Polyester cotton fabric high whiteness high non-ironing short process processing technology 鲁丰织染有限公司 2025-04-04 CN claimed
CN-115872900-B Method for generating and capturing alkyl free radical and product and application of product 深圳湾实验室坪山生物医药研发转化中心 2025-03-18 CN claimed
CN-119569980-A Hydrogen bond-containing COF polymer and preparation method and application thereof 山东师范大学 2025-03-07 CN claimed
CN-119570049-A Preparation method and application of metal organic framework nanosheets 大连理工大学 2025-03-07 CN claimed
US-20250038256-A1 NITRILE ADDITIVES FOR ELECTROLYTES OF BATTERIES INCLUDING LITHIUM- AND MANGANESE-RICH POSITIVE ELECTRODES GM Global Technology Operations LLC 2025-01-30 US claimed
CN-119221275-A Polyester cotton fabric high whiteness high non-ironing short process processing technology 鲁丰织染有限公司 2024-12-31 CN claimed
CN-118653296-A Finishing process of woven spun silk high Bai Hunfang fabric 鲁丰织染有限公司 2024-09-17 CN claimed
CN-117018890-B Polyvinylidene fluoride double-layer composite membrane based on interfacial polymerization and preparation method thereof 贵州省材料产业技术研究院 2024-05-14 CN claimed
CN-118016924-A Elastic sealant for solid oxide fuel cell stack and preparation method thereof 江苏理工学院 2024-05-10 CN claimed
WO-1991016892-A1 STYRYL COMPOUNDS WHICH INHIBIT EGF RECEPTOR PROTEIN TYROSINE KINASE RORER INTERNATIONAL (HOLDINGS), INC. (US) 1991-11-14 WO claimed
US-4948639-A COMPOSITE LAMINATE FABRIC OF MELT BLOWN MATERIAL AND ACTIVE PARTICLES KIMBERLY-CLARK CORPORATION (US) 1990-08-14 US claimed
EP-0326319-A2 Adhesive composition N.V. RAYCHEM S.A. (BE) 1989-08-02 EP claimed
US-4837070-A CELLULOSE WEB WITH RUBBER COATING KIMBERLY-CLARK CORPORATION (US) 1989-06-06 US claimed
US-4810571-A Synthetic sheet composite KIMBERLY-CLARK CORPORATION (US) 1989-03-07 US claimed
US-4797318-A WEAR RESISTANT LAMINATES, BAGS FOR VACUUM CLEANERS KIMBERLY-CLARK CORPORATION (US) 1989-01-10 US claimed
US-4793366-A Nicotine dispensing device and methods of making the same PHARMACIA, INC. 1988-12-27 US claimed
US-4703099-A CATALYTICALLY TRIMERIZING ISOCYANATES THE DOW CHEMICAL COMPANY (US) 1987-10-27 US claimed
US-4632989-A KETENE AMINAL-OLEFIN REACTION PRODUCT AS CATALYSTS THE DOW CHEMICAL COMPANY (US) 1986-12-30 US claimed
US-4536490-A REACTION PRODUCT OF KETENE-AMINAL AND UNSATURATED COMPOUND THE UPJOHN COMPANY (US) 1985-08-20 US claimed