SCHEMBL17466930

SCHEMBL17466930

N#CC(C#N)=Cc1ccc(-c2ccccc2)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 11/20 0.71
KMT2A Q03164 10/20 0.71
ALDH1A1 P00352 10/20 0.71
MEN1 O00255 9/20 0.71
KDM4E B2RXH2 5/20 0.71
LMNA P02545 5/20 0.71
NPSR1 Q6W5P4 3/20 0.71
POLB P06746 1/20 0.71
THRB P10828 1/20 0.61
CISD1 Q9NZ45 1/20 0.61
EGFR P00533 4/20 0.59
HPGD P15428 4/20 0.53
CYP3A4 P08684 3/20 0.53
TSHR P16473 3/20 0.53
NFKB1 P19838 3/20 0.53
BLM P54132 3/20 0.53
PMP22 Q01453 3/20 0.53
CYP1A2 P05177 2/20 0.53
APEX1 P27695 1/20 0.53
TP53 P04637 5/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17466936 0.91 MAPT (0.85) MAPTKMT2AALDH1A1MEN1KDM4E
SCHEMBL880383 0.88 MAPT (0.56) MAPTKMT2AALDH1A1MEN1KDM4E
SCHEMBL60843 0.87 MAPT (0.76) MAPTKMT2AALDH1A1MEN1KDM4E
Hydrochloric Acid SCHEMBL28271363 0.85 MAPT (0.73) MAPTKMT2AALDH1A1MEN1KDM4E
SCHEMBL20824922 0.84 KMT2A (0.80) MAPTKMT2AALDH1A1MEN1KDM4E
SCHEMBL17466932 0.84 MAPT (1.00) MAPTKMT2AALDH1A1MEN1KDM4E
SCHEMBL17466937 0.83 KMT2A (0.71) MAPTKMT2AALDH1A1MEN1KDM4E
SCHEMBL18868872 0.80 MAPT (0.65) MAPTKMT2AALDH1A1MEN1KDM4E
SCHEMBL5496749 0.79 ALDH1A1 (0.63) MAPTKMT2AALDH1A1MEN1KDM4E
SCHEMBL13485333 0.79 ESR1 (0.65) MAPTKMT2AALDH1A1MEN1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122010777-A Method for synthesizing cyclopentane compounds by utilizing bromide ions/visible light synergistic catalysis 南京工业大学 2026-05-12 CN disclosed
EP-3172272-B1 MODIFIED HETEROPHASIC POLYOLEFIN COMPOSITION MILLIKEN & CO (US) 2020-11-25 EP disclosed
US-9410035-B2 Modified heterophasic polyolefin composition MILLIKEN & COMPANY (US) 2016-08-09 US disclosed
US-20160024289-A1 MODIFIED HETEROPHASIC POLYOLEFIN COMPOSITION MILLIKEN & COMPANY 2016-01-28 US disclosed