Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 6/20 | 0.58 |
| ▸ | GSK3A | P49840 | 4/20 | 0.58 |
| ▸ | CDK1 | P06493 | 3/20 | 0.58 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.58 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.58 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.58 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.31 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5099342 | 0.90 | GSK3B (0.66) | GSK3BGSK3ACDK1CCNB2CCNB1 | |
| SCHEMBL5089420 | 0.87 | GSK3B (0.62) | GSK3BGSK3ACDK1CCNB2CCNB1 | |
| SCHEMBL7021655 | 0.83 | GSK3B (0.68) | GSK3BGSK3ACDK1CCNB2CCNB1 | |
| SCHEMBL6086723 | 0.83 | GSK3B (0.68) | GSK3BGSK3ACDK1CCNB2CCNB1 | |
| SCHEMBL5089149 | 0.82 | GSK3B (0.54) | GSK3BGSK3ACDK1CCNB2CCNB1 | |
| SCHEMBL5089237 | 0.81 | GSK3B (0.64) | GSK3BGSK3ACDK1CCNB2CCNB1 | |
| SCHEMBL4400584 | 0.81 | GSK3B (0.85) | GSK3BGSK3ACDK1CCNB2CCNB1 | |
| SCHEMBL5094954 | 0.80 | GSK3B (0.53) | GSK3BGSK3ACDK1CCNB2CCNB1 | |
| SCHEMBL5100153 | 0.79 | GSK3B (0.76) | GSK3BGSK3ACDK1CCNB2CCNB1 | |
| SCHEMBL7254195 | 0.79 | GSK3B (0.84) | GSK3BGSK3ACDK1CCNB2CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7045519-B2 | Inhibitors of glycogen synthase kinase 3 | CHIRON CORPORATION (US) | 2006-05-16 | — | — | US | disclosed |
| US-20020156087-A1 | Inhibitors of glycogen synthase kinase 3 | CHIRON CORPORATION | 2002-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020156087-A1 | Inhibitors of glycogen synthase kinase 3 | GSK3B, GSK3A, PYGB | GSK3B 1/4885GSK3A 2/4885CDK1 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.