Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TPH1 | P17752 | 1/20 | 0.32 |
| ▸ | TPH2 | Q8IWU9 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7854087 | 0.93 | ACKR3 (0.36) | ACKR3 | |
| SCHEMBL6087230 | 0.89 | KMT2A (0.33) | KMT2ATLR7MEN1TDP1TPH1 | |
| SCHEMBL6097406 | 0.87 | ACKR3 (0.38) | ACKR3KMT2ATLR7MEN1TDP1 | |
| SCHEMBL6636863 | 0.85 | GRIN1 (0.44) | KMT2ATLR7TPH1TPH2KDM4E | |
| SCHEMBL6088424 | 0.85 | CYP1A2 (0.38) | KMT2AMEN1TDP1HPGDKDM4E | |
| SCHEMBL10204275 | 0.83 | KMT2A (0.35) | KMT2ATLR7MEN1TDP1KDM5B | |
| SCHEMBL501440 | 0.83 | MEN1 (0.31) | KMT2AMEN1TDP1HPGDKDM4E | |
| SCHEMBL6089258 | 0.82 | KMT2A (0.41) | KMT2ATLR7MEN1HPGDKDM4E | |
| SCHEMBL6088109 | 0.81 | KMT2A (0.37) | KMT2AMEN1TDP1TPH1TPH2 | |
| SCHEMBL6085624 | 0.81 | TYMS (0.36) | KMT2AMEN1TDP1TPH1TPH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6987114-B1 | Antiviral pyrimidinedione derivatives and process for the preparation thereof | SAMJIN PHARMACEUTICAL CO., LTD (KR) | 2006-01-17 | — | — | US | disclosed |