Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8210568 | 0.92 | HPGD (0.39) | KMT2AHPGDMEN1KDM4EPSMD14 | |
| SCHEMBL6088109 | 0.92 | KMT2A (0.37) | KMT2AHPGDMEN1KDM4EPSMD14 | |
| SCHEMBL6634103 | 0.91 | KMT2A (0.38) | KMT2AHPGDMEN1KDM4EHTT | |
| SCHEMBL6086464 | 0.91 | DAO (0.44) | KMT2AHPGDMEN1KDM4EPSMD14 | |
| SCHEMBL6637345 | 0.90 | GAA (0.39) | KMT2AHPGDMEN1KDM4EPSMD14 | |
| SCHEMBL6086806 | 0.89 | KMT2A (0.34) | KMT2AHPGDMEN1KDM4EPSMD14 | |
| SCHEMBL6086784 | 0.89 | ALDH1A1 (0.36) | ALDH1A1MAPT | |
| SCHEMBL6636291 | 0.88 | KMT2A (0.33) | KMT2AHPGDMEN1KDM4EPSMD14 | |
| SCHEMBL6087076 | 0.87 | GRIN1 (0.43) | HPGDKDM4EALDH1A1POLBPKM | |
| SCHEMBL6085657 | 0.87 | GRIN1 (0.36) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6987114-B1 | Antiviral pyrimidinedione derivatives and process for the preparation thereof | SAMJIN PHARMACEUTICAL CO., LTD (KR) | 2006-01-17 | — | — | US | disclosed |