Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7849821 | 0.90 | BRD4 (0.35) | SMN1; SMN2KMT2AALDH1A1MAPK1LMNA | |
| SCHEMBL7758798 | 0.87 | SMN1; SMN2 (0.35) | SMN1; SMN2KMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL7759888 | 0.87 | SMN1; SMN2 (0.35) | SMN1; SMN2KMT2AALDH1A1MAPK1LMNA | |
| SCHEMBL7756725 | 0.87 | SMN1; SMN2 (0.35) | SMN1; SMN2KMT2AALDH1A1MAPK1LMNA | |
| SCHEMBL7756730 | 0.87 | SMN1; SMN2 (0.35) | SMN1; SMN2KMT2AALDH1A1MAPK1LMNA | |
| SCHEMBL7758804 | 0.87 | SMN1; SMN2 (0.35) | SMN1; SMN2KMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL7757638 | 0.85 | SMN1; SMN2 (0.33) | SMN1; SMN2KMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL7757642 | 0.85 | SMN1; SMN2 (0.33) | SMN1; SMN2KMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL6087044 | 0.82 | SMN1; SMN2 (0.37) | SMN1; SMN2KMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL6087870 | 0.82 | SMN1; SMN2 (0.38) | SMN1; SMN2KMT2AALDH1A1MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6987114-B1 | Antiviral pyrimidinedione derivatives and process for the preparation thereof | SAMJIN PHARMACEUTICAL CO., LTD (KR) | 2006-01-17 | — | — | US | disclosed |
| EP-0736015-B1 | ANTIVIRAL 2,4-PYRIMIDINDIONE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | KOREA RES INST CHEM TECH (KR) | 2001-03-07 | — | — | EP | disclosed |
| US-5747500-A | VIRICIDES FOR AIDS | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1998-05-05 | — | — | US | disclosed |