Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TPH1 | P17752 | 1/20 | 0.36 |
| ▸ | TPH2 | Q8IWU9 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6086604 | 0.92 | DRD1 (0.33) | SMN1; SMN2TPH1TPH2HPGDALDH1A1 | |
| SCHEMBL6086132 | 0.92 | TYMS (0.38) | SMN1; SMN2TPH1TPH2HPGDALDH1A1 | |
| SCHEMBL6086259 | 0.92 | GRIN1 (0.37) | SMN1; SMN2TPH1TPH2HPGDALDH1A1 | |
| SCHEMBL6085479 | 0.92 | MTNR1A (0.37) | SMN1; SMN2HPGDALDH1A1KDM4EHSD17B10 | |
| SCHEMBL6086864 | 0.91 | HPGD (0.44) | HPGDALDH1A1KDM4EHSD17B10MEN1 | |
| SCHEMBL10204457 | 0.90 | TPH1 (0.35) | SMN1; SMN2TPH1TPH2HPGDALDH1A1 | |
| SCHEMBL6087627 | 0.89 | TSHR (0.34) | SMN1; SMN2TPH1TPH2HPGDALDH1A1 | |
| SCHEMBL6087014 | 0.86 | DAO (0.46) | HPGDALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL6086483 | 0.86 | MTNR1A (0.50) | ALDH1A1HSD17B10MEN1KMT2ATSHR | |
| SCHEMBL6085671 | 0.85 | GRIN1 (0.44) | HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6987114-B1 | Antiviral pyrimidinedione derivatives and process for the preparation thereof | SAMJIN PHARMACEUTICAL CO., LTD (KR) | 2006-01-17 | — | — | US | disclosed |