Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7851082 | 0.93 | DHODH (0.32) | — | |
| SCHEMBL6088668 | 0.87 | POLB (0.35) | KDM4EALDH1A1HTTTSHRMAPK1 | |
| SCHEMBL6089258 | 0.85 | KMT2A (0.41) | KDM4EALDH1A1HTTCYP3A4HPGD | |
| SCHEMBL6086464 | 0.85 | DAO (0.44) | KDM4EALDH1A1HTTCYP3A4HPGD | |
| SCHEMBL6088109 | 0.82 | KMT2A (0.37) | KDM4EALDH1A1HTTCYP3A4HPGD | |
| SCHEMBL6088424 | 0.82 | CYP1A2 (0.38) | KDM4EALDH1A1CYP1A2CYP3A4HPGD | |
| SCHEMBL10204282 | 0.81 | KMT2A (0.36) | CYP3A4MEN1KMT2ATDP1PARP1 | |
| SCHEMBL6636863 | 0.80 | GRIN1 (0.44) | KDM4EALDH1A1KMT2AGAAPOLB | |
| SCHEMBL12752174 | 0.79 | KMT2A (0.40) | KDM4EALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL6634103 | 0.79 | KMT2A (0.38) | KDM4EALDH1A1HTTHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6987114-B1 | Antiviral pyrimidinedione derivatives and process for the preparation thereof | SAMJIN PHARMACEUTICAL CO., LTD (KR) | 2006-01-17 | — | — | US | disclosed |