Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | HBB | P68871 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7854200 | 0.92 | USP2 (0.36) | KMT2AMEN1TDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL674037 | 0.88 | GRIN1 (0.42) | KMT2AMEN1TDP1GRIN1GRIN2B | |
| SCHEMBL675171 | 0.87 | KMT2A (0.35) | KMT2AMEN1TDP1GRIN1GRIN2B | |
| SCHEMBL6088384 | 0.86 | GRIN1 (0.38) | KMT2AMEN1TDP1GRIN1GRIN2B | |
| SCHEMBL7068410 | 0.86 | GRIN1 (0.38) | KMT2AMEN1TDP1GRIN1GRIN2B | |
| SCHEMBL6086562 | 0.85 | MTOR (0.38) | KMT2AMEN1TDP1GRIN1GRIN2B | |
| SCHEMBL6086536 | 0.84 | KMT2A (0.36) | KMT2AMEN1TDP1GRIN1GRIN2B | |
| SCHEMBL12752174 | 0.83 | KMT2A (0.40) | KMT2AMEN1TDP1TP53SMN1; SMN2 | |
| SCHEMBL12752183 | 0.82 | KMT2A (0.47) | KMT2AMEN1TDP1TP53SMN1; SMN2 | |
| SCHEMBL12752290 | 0.82 | B3GNT2 (0.41) | KMT2AMEN1TDP1GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6987114-B1 | Antiviral pyrimidinedione derivatives and process for the preparation thereof | SAMJIN PHARMACEUTICAL CO., LTD (KR) | 2006-01-17 | — | — | US | disclosed |