SCHEMBL675171

SCHEMBL675171

Cc1cc(C)cc(C(=O)c2c(C(C)C)c(=O)[nH]c(=O)n2CC2CC=CC2)c1

nearest known ligand 0.49

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
GRIN1 Q05586 2/20 0.34
GRIN2B Q13224 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL674037 0.92 GRIN1 (0.42) KMT2AMEN1TDP1GRIN1GRIN2B
SCHEMBL6088384 0.90 GRIN1 (0.38) KMT2AMEN1TDP1GRIN1GRIN2B
SCHEMBL7068410 0.90 GRIN1 (0.38) KMT2AMEN1TDP1GRIN1GRIN2B
SCHEMBL6086562 0.89 MTOR (0.38) KMT2AMEN1TDP1GRIN1GRIN2B
SCHEMBL8340329 0.89 KMT2A (0.36) KMT2AMEN1TDP1GRIN1GRIN2B
SCHEMBL6087585 0.87 KMT2A (0.35) KMT2AMEN1TDP1GRIN1GRIN2B
SCHEMBL675478 0.85 KMT2A (0.35) KMT2AMEN1TDP1GRIN1GRIN2B
SCHEMBL7852090 0.85 GRIN1 (0.37) KMT2AMEN1TDP1GRIN1GRIN2B
SCHEMBL12752174 0.83 KMT2A (0.40) KMT2AMEN1TDP1
SCHEMBL12752325 0.83 GRIN1 (0.35) KMT2AMEN1TDP1GRIN1GRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250255968-A1 INTRAVAGINAL DEVICES FOR DRUG DELIVERY KISER PATRICK F (US) 2025-08-14 US claimed
EP-2734262-B1 INTRAVAGINAL RINGS FOR DRUG DELIVERY KISER PATRICK F (US) 2018-02-28 EP claimed
US-20140209100-A1 INTRAVAGINAL DEVICES FOR DRUG DELIVERY Kiser, Patrick F. 2014-07-31 US claimed
EP-2734262-A1 INTRAVAGINAL DEVICES FOR DRUG DELIVERY Kiser, Patrick F. (US) 2014-05-28 EP claimed
US-20130220337-A1 DEVICES AND METHODS FOR INTRAVAGINAL DELIVERY OF DRUGS AND OTHER SUBSTANCES KISER PATRICK F (US) 2013-08-29 US claimed
EP-2605779-A2 DEVICES AND METHODS FOR INTRAVAGINAL DELIVERY OF DRUGS AND OTHER SUBSTANCES The University of Utah Research Foundation (US) 2013-06-26 EP claimed
WO-2013013172-A1 INTRAVAGINAL DEVICES FOR DRUG DELIVERY THE UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2013-01-24 WO claimed
WO-2012024605-A2 DEVICES AND METHODS FOR INTRAVAGINAL DELIVERY OF DRUGS AND OTHER SUBSTANCES THE UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2012-02-23 WO claimed
US-20110045076-A1 LINEAR ORDER RELEASE POLYMER THE UNIVERSITY OF UTAH RESEARCH FOUNDATION 2011-02-24 US claimed
US-20250255968-A1 INTRAVAGINAL DEVICES FOR DRUG DELIVERY KISER PATRICK F (US) 2025-08-14 US disclosed
EP-2734262-B1 INTRAVAGINAL RINGS FOR DRUG DELIVERY KISER PATRICK F (US) 2018-02-28 EP disclosed
US-20150320675-A1 Modified Release Osmotic Pump for PH-Responsive Drug Delivery NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2015-11-12 US disclosed
US-20140209100-A1 INTRAVAGINAL DEVICES FOR DRUG DELIVERY Kiser, Patrick F. 2014-07-31 US disclosed
WO-2014113693-A1 MODIFIED RELEASE OSMOTIC PUMP FOR PH-RESPONSIVE INTRAVAGINAL DRUG DELIVERY UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2014-07-24 WO disclosed
WO-2012024605-A2 DEVICES AND METHODS FOR INTRAVAGINAL DELIVERY OF DRUGS AND OTHER SUBSTANCES THE UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2012-02-23 WO disclosed
US-20110045076-A1 LINEAR ORDER RELEASE POLYMER THE UNIVERSITY OF UTAH RESEARCH FOUNDATION 2011-02-24 US disclosed
EP-2244782-A2 LINEAR ORDER RELEASE POLYMER The University of Utah Research Foundation (US) 2010-11-03 EP disclosed
WO-2009094573-A9 LINEAR ORDER RELEASE POLYMER THE UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2010-09-16 WO disclosed
WO-2009094573-A2 LINEAR ORDER RELEASE POLYMER THE UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2009-07-30 WO disclosed
US-5922727-A 1-((SUBSTITUTED)CYCLOALK(EN)YLALKYL)-6-((SUB)PHENYL(CARBONYL, SULFIDE, OR OXO))-2,4-PYRIMIDINEDIONE DERIVATIVES HAVING SUPERIOR ANTIVIRAL ACTIVITIES; HIV SAMJIN PHARMACEUTICAL CO., LTD (KR) 1999-07-13 US disclosed