Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | RPA1 | P27694 | 1/20 | 0.36 |
| ▸ | PTGIR | P43119 | 1/20 | 0.35 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7850310 | 0.93 | PDE10A (0.35) | PDE10APTGDR2BRD4RPA1PTGIR | |
| SCHEMBL6088424 | 0.87 | CYP1A2 (0.38) | PDE10APTGDR2BRD4CYP1A2AKR1B1 | |
| SCHEMBL6085740 | 0.83 | KMT2A (0.34) | CYP3A4MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL6097406 | 0.83 | ACKR3 (0.38) | MEN1KMT2AKDM4EFAAHTDP1 | |
| SCHEMBL6086631 | 0.83 | GRIN1 (0.45) | PTGDR2KMT2A | |
| SCHEMBL6087879 | 0.83 | DAO (0.45) | PDE10APTGDR2CYP1A2CYP3A4MEN1 | |
| SCHEMBL6087483 | 0.82 | MEN1 (0.43) | BRD4CYP3A4MEN1KMT2AKDM4E | |
| SCHEMBL6088668 | 0.82 | POLB (0.35) | MEN1KMT2AKDM4EALDH1A1TDP1 | |
| SCHEMBL6086262 | 0.81 | TP53 (0.39) | RPA1AKR1B1MEN1KMT2ANPC1 | |
| SCHEMBL7853459 | 0.81 | CYP1A2 (0.34) | PDE10APTGDR2BRD4CYP1A2AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6987114-B1 | Antiviral pyrimidinedione derivatives and process for the preparation thereof | SAMJIN PHARMACEUTICAL CO., LTD (KR) | 2006-01-17 | — | — | US | disclosed |