Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | TPH1 | P17752 | 1/20 | 0.34 |
| ▸ | TPH2 | Q8IWU9 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6097406 | 0.88 | ACKR3 (0.38) | KMT2AMEN1TPH1TPH2TSHR | |
| SCHEMBL6087230 | 0.86 | KMT2A (0.33) | KMT2AMEN1TPH1TPH2TSHR | |
| SCHEMBL7847583 | 0.85 | TLR7 (0.32) | KMT2AMEN1TPH1TPH2KDM4E | |
| SCHEMBL6086631 | 0.84 | GRIN1 (0.45) | KMT2ATPH1TPH2TLR7 | |
| SCHEMBL6087616 | 0.83 | PDE10A (0.40) | KMT2AMEN1KDM4ECYP3A4TDP1 | |
| SCHEMBL6087483 | 0.83 | MEN1 (0.43) | KMT2AMEN1TSHRKDM4EMAPK1 | |
| SCHEMBL6086113 | 0.80 | TSHR (0.35) | KMT2AMEN1TPH1TPH2TSHR | |
| SCHEMBL6087138 | 0.80 | DRD1 (0.36) | KMT2AMEN1TPH1TPH2TSHR | |
| SCHEMBL6089500 | 0.79 | TPH1 (0.38) | KMT2AMEN1TPH1TPH2TSHR | |
| SCHEMBL6086074 | 0.79 | MEN1 (0.35) | KMT2AMEN1TPH1TPH2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6987114-B1 | Antiviral pyrimidinedione derivatives and process for the preparation thereof | SAMJIN PHARMACEUTICAL CO., LTD (KR) | 2006-01-17 | — | — | US | disclosed |