Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 5/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TPH1 | P17752 | 4/20 | 0.35 |
| ▸ | TPH2 | Q8IWU9 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6087998 | 0.97 | GRIN1 (0.39) | GRIN1GRIN2BMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2466620 | 0.95 | GRIN1 (0.43) | GRIN1GRIN2BMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7070522 | 0.89 | GRIN1 (0.35) | GRIN1GRIN2BMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7850609 | 0.87 | GRIN1 (0.38) | GRIN1GRIN2BMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6086654 | 0.85 | LMNA (0.36) | GRIN1GRIN2BMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6086617 | 0.83 | GRIN1 (0.39) | GRIN1GRIN2BMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7848078 | 0.82 | GRIN1 (0.39) | GRIN1GRIN2BMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7074091 | 0.81 | GRIN1 (0.39) | GRIN1GRIN2BMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6088065 | 0.80 | GRIN1 (0.38) | GRIN1GRIN2BMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7066840 | 0.80 | SMN1; SMN2 (0.30) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6987114-B1 | Antiviral pyrimidinedione derivatives and process for the preparation thereof | SAMJIN PHARMACEUTICAL CO., LTD (KR) | 2006-01-17 | — | — | US | disclosed |