SCHEMBL6088593

SCHEMBL6088593

Nc1ccc(CCC2=NNC(=O)/C2=C/c2cc(Cl)c[nH]2)cc1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GFER P55789 1/20 0.32
DAO P14920 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6088598 1.00 GFER (0.32) GFERDAO
SCHEMBL6089530 0.89 PDPK1 (0.34) DAO
SCHEMBL6089536 0.89 PDPK1 (0.34) DAO
SCHEMBL6089383 0.88 TUBB4A (0.37) DAO
SCHEMBL6089379 0.88 TUBB4A (0.37) DAO
SCHEMBL6091001 0.86 GFER (0.32) GFER
SCHEMBL6090999 0.86 GFER (0.32) GFER
SCHEMBL6090037 0.86 PDPK1 (0.39) GFERDAO
SCHEMBL6089582 0.81 GFER (0.33) GFER
SCHEMBL6089586 0.81 GFER (0.33) GFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7060822-B1 2-pyrazolin-5-ones ABBOTT GMBH & CO. KG (DE) 2006-06-13 US disclosed