Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 6/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6088734 | 1.00 | KDR (0.37) | KDRCHEK1ALDH1A1LMNA | |
| SCHEMBL6088112 | 0.84 | KDR (0.36) | KDRCHEK1ALDH1A1LMNA | |
| SCHEMBL6088104 | 0.84 | KDR (0.36) | KDRCHEK1ALDH1A1LMNA | |
| SCHEMBL6090271 | 0.84 | KDR (0.57) | KDRCHEK1 | |
| SCHEMBL6090299 | 0.84 | KDR (0.57) | KDRCHEK1 | |
| SCHEMBL6090720 | 0.83 | KDR (0.42) | KDRCHEK1ALDH1A1LMNA | |
| SCHEMBL6088520 | 0.83 | KDR (0.39) | KDRCHEK1ALDH1A1LMNA | |
| SCHEMBL6090714 | 0.83 | KDR (0.42) | KDRCHEK1ALDH1A1LMNA | |
| SCHEMBL6088512 | 0.83 | KDR (0.39) | KDRCHEK1ALDH1A1LMNA | |
| SCHEMBL6088316 | 0.83 | KDR (0.39) | KDRCHEK1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7060822-B1 | 2-pyrazolin-5-ones | ABBOTT GMBH & CO. KG (DE) | 2006-06-13 | — | — | US | disclosed |