Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 2/20 | 0.34 |
| ▸ | RARB | P10826 | 2/20 | 0.34 |
| ▸ | RARG | P13631 | 2/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6086714 | 0.79 | PDK2 (0.34) | RARARARBRARG | |
| SCHEMBL6087866 | 0.76 | PDE4B (0.36) | RARARARBRARG | |
| SCHEMBL6088929 | 0.73 | KDM4E (0.36) | RARARARBRARG | |
| SCHEMBL6552888 | 0.72 | RARA (0.34) | RARARARBRARG | |
| SCHEMBL7773429 | 0.72 | — | — | |
| SCHEMBL6297202 | 0.71 | RARB (0.51) | RARARARBRARG | |
| SCHEMBL6292648 | 0.71 | RARA (0.43) | RARARARBRARG | |
| SCHEMBL6088924 | 0.70 | RARB (0.34) | RARARARBRARG | |
| SCHEMBL7731139 | 0.69 | RARA (0.35) | RARARARBRARG | |
| SCHEMBL2863971 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7026487-B2 | Amines substituted with a dihydronaphthalenyl, chromenyl, or thiochromenyl group, a pyridyl group and an alkyl group, having retinoid-like biological activity | ALLERGAN, INC. (US) | 2006-04-11 | — | — | US | disclosed |