Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6091810 | 0.80 | CHEK1 (0.38) | CHEK1KDR | |
| SCHEMBL6090985 | 0.80 | CHEK1 (0.37) | CHEK1KDR | |
| SCHEMBL6090679 | 0.78 | CHEK1 (0.49) | CHEK1KDR | |
| SCHEMBL6089565 | 0.78 | KDR (0.46) | CHEK1KDR | |
| SCHEMBL6089563 | 0.78 | KDR (0.46) | CHEK1KDR | |
| SCHEMBL6089341 | 0.77 | KDR (0.46) | CHEK1KDR | |
| SCHEMBL6090620 | 0.77 | CHEK1 (0.38) | CHEK1KDR | |
| SCHEMBL6090616 | 0.77 | CHEK1 (0.38) | CHEK1KDR | |
| SCHEMBL6089074 | 0.77 | KDR (0.59) | CHEK1KDR | |
| SCHEMBL6090284 | 0.77 | CHEK1 (0.47) | CHEK1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7060822-B1 | 2-pyrazolin-5-ones | ABBOTT GMBH & CO. KG (DE) | 2006-06-13 | — | — | US | disclosed |
| EP-1218373-A2 | 2-PYRAZOLIN-5-ONES AS TYROSINE KINASE INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001009121-A2 | 2-PYRAZOLIN-5-ONES_AS TYROSINE KINASE INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 2001-02-08 | — | — | WO | disclosed |