Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.48 |
| ▸ | SERPINE1 | P05121 | 5/20 | 0.47 |
| ▸ | ICMT | O60725 | 4/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6091286 | 0.98 | PPARG (0.51) | PPARGSERPINE1ICMTMAOB | |
| SCHEMBL5750659 | 0.95 | SERPINE1 (0.47) | PPARGSERPINE1ICMT | |
| SCHEMBL6090091 | 0.93 | PPARG (0.57) | PPARGSERPINE1ICMTMAOB | |
| SCHEMBL6092537 | 0.93 | PPARG (0.59) | PPARGSERPINE1MAOB | |
| SCHEMBL6093344 | 0.84 | PPARG (0.65) | PPARGSERPINE1ICMT | |
| SCHEMBL6092341 | 0.84 | PPARG (0.54) | PPARGICMTMAOB | |
| SCHEMBL6091159 | 0.84 | PPARG (0.65) | PPARGSERPINE1ICMT | |
| SCHEMBL6092255 | 0.81 | ICMT (0.48) | PPARGSERPINE1ICMT | |
| SCHEMBL6093097 | 0.81 | SERPINE1 (0.51) | PPARGSERPINE1ICMT | |
| SCHEMBL6091701 | 0.80 | SERPINE1 (0.49) | PPARGSERPINE1ICMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060160879-A1 | Indoles useful in the treatment of inflammation | BIOLIPOX AB (SE) | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160879-A1 | Indoles useful in the treatment of inflammation | IDO1, PTGS1, IDO2 | PPARG 481/4885SERPINE1 508/4885ICMT 1525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.