Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR8 | P51685 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 5/20 | 0.40 |
| ▸ | FABP1 | P07148 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SERPINE1 | P05121 | 3/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ICMT | O60725 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6092494 | 0.90 | SERPINE1 (0.47) | CCR8FAAHPPARGFABP1MEN1 | |
| SCHEMBL5751151 | 0.85 | FAAH (0.39) | CCR8FAAHPPARGFABP1MEN1 | |
| SCHEMBL6091753 | 0.81 | SERPINE1 (0.57) | FAAHPPARGFABP1SERPINE1PPARA | |
| SCHEMBL6091399 | 0.77 | SERPINE1 (0.46) | FAAHPPARGFABP1SERPINE1PPARA | |
| SCHEMBL6091749 | 0.76 | MAPT (0.47) | MEN1KMT2A | |
| SCHEMBL19159661 | 0.75 | TSHR (0.53) | TSHRTP53 | |
| SCHEMBL13168309 | 0.74 | SERPINE1 (0.49) | PPARGKMT2ASERPINE1TP53 | |
| SCHEMBL2808138 | 0.73 | SERPINE1 (0.47) | PPARGKMT2ASERPINE1 | |
| SCHEMBL14019802 | 0.73 | TSHR (0.54) | MEN1KMT2ATSHR | |
| SCHEMBL2808118 | 0.72 | SERPINE1 (0.49) | PPARGSERPINE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060160879-A1 | Indoles useful in the treatment of inflammation | BIOLIPOX AB (SE) | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160879-A1 | Indoles useful in the treatment of inflammation | IDO1, PTGS1, IDO2 | CCR8 1101/4885FAAH 435/4885PPARG 481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.