Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 11/20 | 0.57 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.57 |
| ▸ | CYSLTR2 | Q9NS75 | 8/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6088320 | 0.94 | CYSLTR1 (0.59) | CYSLTR1GPBAR1CYSLTR2ALOX5 | |
| SCHEMBL6089080 | 0.94 | CYSLTR1 (0.59) | CYSLTR1GPBAR1CYSLTR2ALOX5 | |
| SCHEMBL6088634 | 0.94 | CYSLTR1 (0.58) | CYSLTR1GPBAR1CYSLTR2ALOX5 | |
| SCHEMBL27528607 | 0.91 | ALOX5 (0.57) | CYSLTR1GPBAR1CYSLTR2ALOX5 | |
| SCHEMBL6089493 | 0.90 | ALOX5 (0.55) | CYSLTR1GPBAR1CYSLTR2ALOX5 | |
| SCHEMBL9023234 | 0.89 | CYSLTR1 (0.65) | CYSLTR1GPBAR1CYSLTR2ALOX5 | |
| SCHEMBL6091338 | 0.89 | CYSLTR1 (0.61) | CYSLTR1GPBAR1CYSLTR2ALOX5MAPT | |
| SCHEMBL10533300 | 0.87 | CYSLTR1 (0.57) | CYSLTR1GPBAR1CYSLTR2ALOX5 | |
| SCHEMBL6089926 | 0.87 | CYSLTR1 (0.61) | CYSLTR1GPBAR1CYSLTR2ALOX5MAPT | |
| SCHEMBL6087522 | 0.86 | CYSLTR1 (0.60) | CYSLTR1GPBAR1CYSLTR2ALOX5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7005440-B1 | Therapeutic uses of tri-aryl acid derivatives | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2006-02-28 | — | — | US | disclosed |
| EP-1177176-A1 | TRI-ARYL ACID DERIVATIVES AS PPAR RECEPTOR LIGANDS | Aventis Pharma Deutschland GmbH (DE) | 2002-02-06 | — | — | EP | disclosed |
| WO-2000064876-A1 | TRI-ARYL ACID DERIVATIVES AS PPAR RECEPTOR LIGANDS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2000-11-02 | — | — | WO | disclosed |