Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 5/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | FABP4 | P15090 | 2/20 | 0.35 |
| ▸ | EDNRB | P24530 | 1/20 | 0.34 |
| ▸ | EDNRA | P25101 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | FABP3 | P05413 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6093147 | 0.88 | GRIN1 (0.41) | GRIN1GRIN2BPTGESTP53CCR2 | |
| SCHEMBL6091649 | 0.87 | GRIN1 (0.41) | GRIN1GRIN2BPTGESTP53CCR2 | |
| SCHEMBL6091659 | 0.87 | GRIN1 (0.41) | GRIN1GRIN2BPTGESTP53CCR2 | |
| SCHEMBL6089799 | 0.84 | GRIN1 (0.43) | GRIN1GRIN2BPTGESCCR2POLB | |
| SCHEMBL6089800 | 0.84 | GRIN1 (0.43) | GRIN1GRIN2BPTGESCCR2POLB | |
| SCHEMBL6091396 | 0.82 | P2RX7 (0.42) | GRIN1GRIN2BPTGESTP53CCR2 | |
| SCHEMBL6092278 | 0.82 | P2RX7 (0.42) | GRIN1GRIN2BPTGESTP53CCR2 | |
| SCHEMBL6092264 | 0.82 | P2RX7 (0.42) | GRIN1GRIN2BPTGESTP53CCR2 | |
| SCHEMBL6090737 | 0.82 | GRIN1 (0.45) | GRIN1GRIN2BPTGESTP53CCR2 | |
| SCHEMBL6093252 | 0.82 | GRIN1 (0.45) | GRIN1GRIN2BPTGESTP53CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060160879-A1 | Indoles useful in the treatment of inflammation | BIOLIPOX AB (SE) | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160879-A1 | Indoles useful in the treatment of inflammation | IDO1, PTGS1, IDO2 | GRIN1 1424/4885GRIN2B 2380/4885PTGES 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.